p53 and MDM2 proteins-interaction-inhibitor chiral

Modify Date: 2024-01-02 16:27:45

p53 and MDM2 proteins-interaction-inhibitor chiral Structure
p53 and MDM2 proteins-interaction-inhibitor chiral structure
Common Name p53 and MDM2 proteins-interaction-inhibitor chiral
CAS Number 939981-37-0 Molecular Weight 734.75400
Density 1.24g/cm3 Boiling Point 788.563ºC at 760 mmHg
Molecular Formula C40H49Cl2N5O4 Melting Point N/A
MSDS N/A Flash Point 430.708ºC

 Use of p53 and MDM2 proteins-interaction-inhibitor chiral


p53 and MDM2 proteins-interaction-inhibitor (chiral) (Compound 32) is an inhibitor of the interaction between p53 and MDM2 proteins.

 Names

Name 2-[4-[(4S,5R)-2-(4-tert-butyl-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dimethylimidazole-1-carbonyl]piperazin-1-yl]-1-morpholin-4-ylethanone
Synonym More Synonyms

  Biological Activity

Description p53 and MDM2 proteins-interaction-inhibitor (chiral) (Compound 32) is an inhibitor of the interaction between p53 and MDM2 proteins.
Related Catalog
References

[1]. Chen R, et al. A Fusion Protein of the p53 Transaction Domain and the p53-Binding Domain of the Oncoprotein MdmX as an Efficient System for High-Throughput Screening of MdmX Inhibitors. Biochemistry. 2017 Jun 27;56(25):3273-3282.

 Chemical & Physical Properties

Density 1.24g/cm3
Boiling Point 788.563ºC at 760 mmHg
Molecular Formula C40H49Cl2N5O4
Molecular Weight 734.75400
Flash Point 430.708ºC
Exact Mass 733.31600
PSA 77.92000
LogP 6.36620
Storage condition 2-8℃

 Synonyms

p53 and MDM2 proteins-interaction-inhibitor chiral
CS-0332
p53 and MDM2 proteins-interaction-inhibitor racemic
CS-0331
2-[4-[[(4S,5R)-4,5-Bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)ethanone
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