Sappanchalcone structure
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Common Name | Sappanchalcone | ||
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CAS Number | 94344-54-4 | Molecular Weight | 286.279 | |
Density | 1.4±0.1 g/cm3 | Boiling Point | 581.7±50.0 °C at 760 mmHg | |
Molecular Formula | C16H14O5 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 221.0±23.6 °C |
Use of SappanchalconeSappanchalcone, a flavonoid isolated from Caesalpinia sappan L., induces caspase-dependent and AIF-dependent apoptosis in human colon cancer cells[1]. |
Name | sappanchalcone |
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Synonym | More Synonyms |
Description | Sappanchalcone, a flavonoid isolated from Caesalpinia sappan L., induces caspase-dependent and AIF-dependent apoptosis in human colon cancer cells[1]. |
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Related Catalog | |
In Vitro | Sappanchalcone has a statistically significant effect on HCT116 cells than on SW480 cells (IC50= 37.33 μM and 54.23 μM, respectively). Sappanchalcone reduces MMP with a significant increase in ROS levels in human colon cancer cells. Sappanchalcone triggered phosphorylation of p53, which is involved in the activation of caspases and increased expression of Bax in HCT116 cells[1]. |
References |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 581.7±50.0 °C at 760 mmHg |
Molecular Formula | C16H14O5 |
Molecular Weight | 286.279 |
Flash Point | 221.0±23.6 °C |
Exact Mass | 286.084137 |
PSA | 86.99000 |
LogP | 2.51 |
Vapour Pressure | 0.0±1.7 mmHg at 25°C |
Index of Refraction | 1.684 |
Hazard Codes | Xi |
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HS Code | 2914509090 |
HS Code | 2914509090 |
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Summary | HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
(2E)-3-(3,4-Dihydroxyphenyl)-1-(4-hydroxy-2-methoxyphenyl)-2-propen-1-one |
2-Propen-1-one, 3-(3,4-dihydroxyphenyl)-1-(4-hydroxy-2-methoxyphenyl)-, (E)- |
2'-Methoxy-3,4,4'-trihydroxychalcone |
3,4,4'-Trihydroxy-2'-methoxychalcone |
sapphalcone |
(E)-3-(3,4-dihydroxyphenyl)-1-(4-hydroxy-2-methoxyphenyl)prop-2-en-1-one |
2-Propen-1-one, 3-(3,4-dihydroxyphenyl)-1-(4-hydroxy-2-methoxyphenyl)-, (2E)- |
Sappan chalcone |