- BioBioPha
- China
- Product Name: Sappanchalcone
- Price: ￥3400.0/5mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Xueping-Zheng
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Sappanchalcone
- Price: ￥4640.0/5mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Sappanchalcone
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: SAPPANCHALCONE
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
94344-54-4
94344-54-4 structure
- Name: Sappanchalcone
- Chemical Name: sappanchalcone
- CAS Number: 94344-54-4
- Molecular Formula: C16H14O5
- Molecular Weight: 286.279
- Catalog: Natural product Chalcone
- Create Date: 2018-07-24 18:48:11
- Modify Date: 2024-01-02 15:19:18
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Sappanchalcone, a flavonoid isolated from Caesalpinia sappan L., induces caspase-dependent and AIF-dependent apoptosis in human colon cancer cells[1].
| Name | sappanchalcone |
|---|---|
| Synonyms |
(2E)-3-(3,4-Dihydroxyphenyl)-1-(4-hydroxy-2-methoxyphenyl)-2-propen-1-one
2-Propen-1-one, 3-(3,4-dihydroxyphenyl)-1-(4-hydroxy-2-methoxyphenyl)-, (E)- 2'-Methoxy-3,4,4'-trihydroxychalcone 3,4,4'-Trihydroxy-2'-methoxychalcone sapphalcone (E)-3-(3,4-dihydroxyphenyl)-1-(4-hydroxy-2-methoxyphenyl)prop-2-en-1-one 2-Propen-1-one, 3-(3,4-dihydroxyphenyl)-1-(4-hydroxy-2-methoxyphenyl)-, (2E)- Sappan chalcone |
| Description | Sappanchalcone, a flavonoid isolated from Caesalpinia sappan L., induces caspase-dependent and AIF-dependent apoptosis in human colon cancer cells[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Sappanchalcone has a statistically significant effect on HCT116 cells than on SW480 cells (IC50= 37.33 μM and 54.23 μM, respectively). Sappanchalcone reduces MMP with a significant increase in ROS levels in human colon cancer cells. Sappanchalcone triggered phosphorylation of p53, which is involved in the activation of caspases and increased expression of Bax in HCT116 cells[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 581.7±50.0 °C at 760 mmHg |
| Molecular Formula | C16H14O5 |
| Molecular Weight | 286.279 |
| Flash Point | 221.0±23.6 °C |
| Exact Mass | 286.084137 |
| PSA | 86.99000 |
| LogP | 2.51 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.684 |
| Hazard Codes | Xi |
|---|---|
| HS Code | 2914509090 |
| HS Code | 2914509090 |
|---|---|
| Summary | HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |