Velagliflozin

Modify Date: 2024-01-04 10:39:31

Velagliflozin Structure
Velagliflozin structure
Common Name Velagliflozin
CAS Number 946525-65-1 Molecular Weight 395.448
Density 1.4±0.1 g/cm3 Boiling Point 648.6±55.0 °C at 760 mmHg
Molecular Formula C23H25NO5 Melting Point N/A
MSDS N/A Flash Point 346.1±31.5 °C

 Use of Velagliflozin


Velagliflozin is an orally available sodium-glucose cotransporter 2 (SGLT2) inhibitor, with anti-diabetic activity.

 Names

Name velagliflozin
Synonym More Synonyms

 Velagliflozin Biological Activity

Description Velagliflozin is an orally available sodium-glucose cotransporter 2 (SGLT2) inhibitor, with anti-diabetic activity.
Related Catalog
Target

SGLT2[1]

In Vitro Velagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, with anti-diabetic activity[1].
In Vivo Velagliflozin (1 mg/kg, p.o.) increases cholesterol, albumin, beta-hydroxybutyrate (BHB), nonesterified fatty acids (NEFA), and urinary glucose excretion, and decreases respiratory exchange ratio in cats[1].
References

[1]. Hoenig M, et al. Effects of the sodium-glucose cotransporter 2 (SGLT2) inhibitor velagliflozin, a new drug with therapeutic potential to treat diabetes in cats. J Vet Pharmacol Ther. 2018 Apr;41(2):266-273.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 648.6±55.0 °C at 760 mmHg
Molecular Formula C23H25NO5
Molecular Weight 395.448
Flash Point 346.1±31.5 °C
Exact Mass 395.173279
LogP 3.87
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.670
Storage condition -20°C

 Synonyms

velagliflozin
(1S)-1,5-Anhydro-1-[4-cyano-3-(4-cyclopropylbenzyl)phenyl]-D-glucitol
UNII:FV2YU8SL0P
D-Glucitol, 1,5-anhydro-1-C-[4-cyano-3-[(4-cyclopropylphenyl)methyl]phenyl]-, (1S)-