Velagliflozin proline hydrate structure
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Common Name | Velagliflozin proline hydrate | ||
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CAS Number | 1661838-94-3 | Molecular Weight | 528.59 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C28H36N2O8 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Velagliflozin proline hydrateVelagliflozin proline hydrate is the clinical form of Velagliflozin (HY-109018). Velagliflozin is an oral sodium-glucose cotransporter 2 (SGLT2) inhibitor with antidiabetic activity. Velagliflozin reduces renal glucose reabsorption and stimulates glycosuria, which lowers blood sugar and insulin concentrations[1]. |
Name | Velagliflozin proline hydrate |
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Description | Velagliflozin proline hydrate is the clinical form of Velagliflozin (HY-109018). Velagliflozin is an oral sodium-glucose cotransporter 2 (SGLT2) inhibitor with antidiabetic activity. Velagliflozin reduces renal glucose reabsorption and stimulates glycosuria, which lowers blood sugar and insulin concentrations[1]. |
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Related Catalog | |
Target |
SGLT2 |
In Vitro | Velagliflozin proline hydrate 是一种钠-葡萄糖共转运蛋白 2 (SGLT2) 抑制剂,具有抗糖尿病活性[1]。 |
In Vivo | Velagliflozin proline hydrate (1 mg/kg, 口服, 单剂量) 增加胆固醇、白蛋白、β -羟基丁酸 (BHB)、非酯化脂肪酸 (NEFA) 和尿葡萄糖排泄,并降低猫的呼吸交换比率[1]。 Velagliflozin proline hydrate (0.3 mg/kg; 口服; 每天 1 次, 共 18 天) 耐受性良好,可通过降低饮食非结构性碳水化合物 (NSC) 的高胰岛素反应来治疗小马的胰岛素失调和预防椎板炎[2]。 |
References |
Molecular Formula | C28H36N2O8 |
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Molecular Weight | 528.59 |