7-Aminocephalosporanic acid structure
|
Common Name | 7-Aminocephalosporanic acid | ||
|---|---|---|---|---|
| CAS Number | 957-68-6 | Molecular Weight | 272.278 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 560.6±50.0 °C at 760 mmHg | |
| Molecular Formula | C10H12N2O5S | Melting Point | >300 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 292.9±30.1 °C | |
| Symbol |
GHS08 |
Signal Word | Danger | |
Use of 7-Aminocephalosporanic acid7-Aminocephalosporanic acid is the core chemical structure for the synthesis of cephalosporin antibiotics, is a potent β-lactamase inhibitor. |
| Name | 7β-aminocephalosporanic acid |
|---|---|
| Synonym | More Synonyms |
| Description | 7-Aminocephalosporanic acid is the core chemical structure for the synthesis of cephalosporin antibiotics, is a potent β-lactamase inhibitor. |
|---|---|
| Related Catalog |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 560.6±50.0 °C at 760 mmHg |
| Melting Point | >300 °C(lit.) |
| Molecular Formula | C10H12N2O5S |
| Molecular Weight | 272.278 |
| Flash Point | 292.9±30.1 °C |
| Exact Mass | 272.046692 |
| PSA | 135.23000 |
| LogP | -0.80 |
| Vapour Pressure | 0.0±3.3 mmHg at 25°C |
| Index of Refraction | 1.661 |
| Storage condition | 2-8°C |
| Symbol |
GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H317-H334 |
| Precautionary Statements | P261-P280-P342 + P311 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn,Xi |
| Risk Phrases | R42/43:May cause sensitization by inhalation and skin contact . R36/37/38:Irritating to eyes, respiratory system and skin . R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . |
| Safety Phrases | S22-S36/37-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2934996000 |
| Precursor 5 | |
|---|---|
| DownStream 9 | |
| HS Code | 2934996000 |
|---|---|
| Summary | 2934996000. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:6.0%. General tariff:20.0% |
|
Construction of recombinant Escherichia coli D11/pMSTO and its use in enzymatic preparation of 7-aminocephalosporanic acid in one pot.
J. Biotechnol. 129(3) , 400-5, (2007) The main drawback in the industrial production of 7-aminocephalosporanic acid is the accumulation of intermediate (AKA-7-ACA) and destruction of substrate (cephalosporin C) catalyzed by catalase and b... |
|
|
Batch production of deacetyl 7-aminocephalosporanic acid by immobilized cephalosporin-C deacetylase.
Appl. Microbiol. Biotechnol. 65(3) , 263-7, (2004) Bacillus subtilis SHS0133 cephalosporin-C deacetylase (CAH) overexpressed in Escherichia coli was immobilized on an anion-exchange resin, KA-890, using glutaraldehyde. The activity yield of immobilize... |
|
|
Site-specific protonation microequilibria of penicillin and cephalosporin beta-lactam core molecules.
Eur. J. Pharm. Sci. 32(1) , 1-7, (2007) Acid-base chemistry of 6-aminopenicillanic acid (6-APA) and 7-aminocephalosporanic acid (7-ACA), the fundamental units of the two classical antibiotic families is characterised at the macroscopic and ... |
| 7-ACS |
| (7R)-7-Aminocephalosporanic acid |
| EINECS 213-485-0 |
| 7-AMINO CEPHALOSPORIC ACID |
| (6R,7R)-3-(Acetoxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-amino-8-oxo-, (6R,7R)- |
| 7beta-aminocephalosporanic acid |
| 7β-aminocephalosporanic acid zwitterion |
| 3-Acetoxymethyl-7-aminoceph-3-em-4-oic Acid |
| 7β-aminocephalosporanic acid |
| 7-Amino |
| MFCD00005177 |
| 7-Aminocephalosporanicacid |
| 7-Aminocephalsporanic acid |
| 7-Aminocephalosporanic acid |
| 7-ACA |
| (6R,7R)-3-[(acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| 7-Amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Acetate Ester |
| Cefazolin Impurity 1 |