BR351
Modify Date: 2025-08-24 12:55:36
BR351 structure
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Common Name | BR351 | ||
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| CAS Number | 960113-85-3 | Molecular Weight | 424.49 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H25FN2O5S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BR351BR351 is a brain penetrant MMP inhibitor with IC50s of 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13, respectively[1]. Potential tools for the molecular imaging of activated MMPs with PET[2]. |
| Name | BR351 |
|---|
| Description | BR351 is a brain penetrant MMP inhibitor with IC50s of 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13, respectively[1]. Potential tools for the molecular imaging of activated MMPs with PET[2]. |
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| Related Catalog | |
| Target |
MMP-9:11 nM (IC50) MMP-2:4 nM (IC50) MMP-8:2 nM (IC50) MMP13:50 nM (IC50) |
| In Vivo | [18F]BR351 Is quickly metabolized in plasma with 20.28% ± 5.41% of intact tracer remaining at 15 minutes postinjection[2]. |
| References |
| Molecular Formula | C20H25FN2O5S |
|---|---|
| Molecular Weight | 424.49 |
| Hazard Codes | Xi |
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