Biotin-PEG9-amine

Modify Date: 2024-04-03 17:26:19

Biotin-PEG9-amine Structure
Biotin-PEG9-amine structure
Common Name Biotin-PEG9-amine
CAS Number 960132-48-3 Molecular Weight 682.86700
Density N/A Boiling Point N/A
Molecular Formula C30H58N4O11S Melting Point N/A
MSDS USA Flash Point N/A

 Use of Biotin-PEG9-amine


Biotin-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]pentanamide
Synonym More Synonyms

 Biotin-PEG9-amine Biological Activity

Description Biotin-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

 Chemical & Physical Properties

Molecular Formula C30H58N4O11S
Molecular Weight 682.86700
Exact Mass 682.38200
PSA 211.60000
LogP 1.44590

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Synonyms

MFCD08274600