Sophoraflavanone G
Modify Date: 2024-01-02 10:26:52
Sophoraflavanone G structure
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Common Name | Sophoraflavanone G | ||
|---|---|---|---|---|
| CAS Number | 97938-30-2 | Molecular Weight | 424.486 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 659.3±55.0 °C at 760 mmHg | |
| Molecular Formula | C25H28O6 | Melting Point | 173-175℃ | |
| MSDS | N/A | Flash Point | 224.8±25.0 °C | |
Use of Sophoraflavanone GSophoraflavanone G (Kushenol F) is iaolated from Sophora flavescens and shows anti-tumor and anti-inflammatory properties. Sophoraflavanone G (Kushenol F) induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways[1][2]. |
| Name | sophoraflavanone G |
|---|---|
| Synonym | More Synonyms |
| Description | Sophoraflavanone G (Kushenol F) is iaolated from Sophora flavescens and shows anti-tumor and anti-inflammatory properties. Sophoraflavanone G (Kushenol F) induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways[1][2]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 29.7 μM (MDA-MB-231 cell)[1] |
| In Vitro | Sophoraflavanone G (0 -100 μM; 24 hours) decreases the viability of the HL-60 cells in a dose-dependent manner[1]. Sophoraflavanone G (0 -100 μM; 24 hours) induces HL-60 cell apoptosis, activated caspase-3 and caspase-9, and downregulated Bcl-2 and Bcl-xL. It also upregulates Bax and released cytochrome c from the mitochondria into the cytoplasm, enabling apoptosis via the mitochondrially-mediated "intrinsic" pathway[1] Sophoraflavanone G (0 -40 μM; 24 hours) inhibits MDA-MB-231 cell viability in a concentration-dependent manner, with an IC50 value of 29.7 ± 5.2 μM[2]<.br> |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 659.3±55.0 °C at 760 mmHg |
| Melting Point | 173-175℃ |
| Molecular Formula | C25H28O6 |
| Molecular Weight | 424.486 |
| Flash Point | 224.8±25.0 °C |
| Exact Mass | 424.188599 |
| PSA | 107.22000 |
| LogP | 6.52 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.623 |
| Storage condition | 2-8℃ |
| Hazard Codes | Xi |
|---|
| 4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-8-[(2R)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-, (2S)- |
| Sophoraflavanone G |
| (2S)-2-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-8-[(2R)-2-isopropenyl-5-methyl-4-hexen-1-yl]-2,3-dihydro-4H-chromen-4-one |
| Kushenol F |
| Norkurarinone |
| Vexibinol |
| Nor-kurarinone |
- BioBioPha
- China
- Product Name: Sophoraflavanone G
- Price: ￥Inquiry/5mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Xueping-Zheng
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Sophoraflavanone G
- Price: ￥3520.0/5mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Liu jia
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: SOPHORAFLAVANONE G
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
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Price: ￥1190/5 mg
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