Adenosine 5'-triphosphate disodium salt

Modify Date: 2024-01-02 15:58:18

Adenosine 5'-triphosphate disodium salt structure	Common Name	Adenosine 5'-triphosphate disodium salt
	CAS Number	987-65-5	Molecular Weight	551.145
	Density	2.63g/cm3	Boiling Point	951.4ºC at 760mmHg
	Molecular Formula	C₁₀H₁₄N₅Na₂O₁₃P₃	Melting Point	188-190ºC
	MSDS	N/A	Flash Point	N/A

Use of Adenosine 5'-triphosphate disodium salt

ATP is a phosphate-group donor for substrate activation in metabolic reactions and the coenzyme for a large number of kinases.

Name	adenosine triphosphate disodium
Synonym	More Synonyms

Description	ATP is a phosphate-group donor for substrate activation in metabolic reactions and the coenzyme for a large number of kinases.
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> P2X Receptor Natural Products >> Alkaloid Research Areas >> Metabolic Disease
References	[1]. Gordon, J.L., Extracellular ATP: effects, sources and fate. Biochem J, 1986. 233(2): p. 309-19. [2]. Guibert, C., et al., Dependence of P2-nucleotide receptor agonist-mediated endothelium-independent relaxation on ectonucleotidase activity and A2A-receptors in rat portal vein. Br J Pharmacol, 1998. 123(8): p. 1732-40. [3]. Burnstock, G., Historical review: ATP as a neurotransmitter. Trends Pharmacol Sci, 2006. 27(3): p. 166-76.

Description

ATP is a phosphate-group donor for substrate activation in metabolic reactions and the coenzyme for a large number of kinases.

Related Catalog

Signaling Pathways >> Membrane Transporter/Ion Channel >> P2X Receptor

Natural Products >> Alkaloid

Research Areas >> Metabolic Disease

References

[1]. Gordon, J.L., Extracellular ATP: effects, sources and fate. Biochem J, 1986. 233(2): p. 309-19.

[2]. Guibert, C., et al., Dependence of P2-nucleotide receptor agonist-mediated endothelium-independent relaxation on ectonucleotidase activity and A2A-receptors in rat portal vein. Br J Pharmacol, 1998. 123(8): p. 1732-40.

[3]. Burnstock, G., Historical review: ATP as a neurotransmitter. Trends Pharmacol Sci, 2006. 27(3): p. 166-76.

Density	2.63g/cm3
Boiling Point	951.4ºC at 760mmHg
Melting Point	188-190ºC
Molecular Formula	C₁₀H₁₄N₅Na₂O₁₃P₃
Molecular Weight	551.145
Exact Mass	550.959656
PSA	314.22000
Water Solubility	H2O: 50 mg/mL

Adenosine 5'-triphosphate disodium salt MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AU7417000

CHEMICAL NAME :: Adenosine 5'-(tetrahydrogen triphosphate), disodium salt

CAS REGISTRY NUMBER :: 987-65-5

LAST UPDATED :: 199706

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C10-H14-N5-O13-P3.2Na

MOLECULAR WEIGHT :: 551.18

WISWESSER LINE NOTATION :: T56 BN DN FN HNJ IZ D- BT5OTJ CQ DQ E1OPQO&OPQO&OPQQO &-NA- 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,20,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,20,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 380 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,20,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,20,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,20,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 266 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,20,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9988 No. of Facilities: 45 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 308 (estimated) No. of Female Employees: 209 (estimated)

Personal Protective Equipment	Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	AU7417000

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