Adenosine 5'-triphosphate disodium salt

Adenosine 5'-triphosphate disodium salt Structure
Adenosine 5'-triphosphate disodium salt structure
Common Name Adenosine 5'-triphosphate disodium salt
CAS Number 987-65-5 Molecular Weight 551.145
Density 2.63g/cm3 Boiling Point 951.4ºC at 760mmHg
Molecular Formula C10H14N5Na2O13P3 Melting Point 188-190ºC
MSDS N/A Flash Point N/A

Quantitative phospho-proteomics reveals the Plasmodium merozoite triggers pre-invasion host kinase modification of the red cell cytoskeleton.

Sci. Rep. 6 , 19766, (2016)

The invasive blood-stage malaria parasite - the merozoite - induces rapid morphological changes to the target erythrocyte during entry. However, evidence for active molecular changes in the host cell that accompany merozoite invasion is lacking. Here, we use ...

Induction of Posttranslational Modifications of Mitochondrial Proteins by ATP Contributes to Negative Regulation of Mitochondrial Function.

PLoS ONE 11 , e0150454, (2016)

It is generally accepted that ATP regulates mitochondrial function through the AMPK signaling pathway. However, the AMPK-independent pathway remains largely unknown. In this study, we investigated ATP surplus in the negative regulation of mitochondrial functi...

DRAM1 regulates autophagy flux through lysosomes.

PLoS ONE 8 , e63245, (2013)

We have previously reported that the mitochondria inhibitor 3-nitropropionic acid (3-NP), induces the expression of DNA damage-regulated autophagy modulator1 (DRAM1) and activation of autophagy in rat striatum. Although the role of DRAM1 in autophagy has been...

A Novel Epigenetic Silencing Pathway Involving the Highly Conserved 5'-3' Exoribonuclease Dhp1/Rat1/Xrn2 in Schizosaccharomyces pombe.

PLoS Genet. 12 , e1005873, (2016)

Epigenetic gene silencing plays a critical role in regulating gene expression and contributes to organismal development and cell fate acquisition in eukaryotes. In fission yeast, Schizosaccharomyces pombe, heterochromatin-associated gene silencing is known to...

Discovery of benzylidene derivatives as potent Syk inhibitors: synthesis, SAR analysis, and biological evaluation.

Arch. Pharm. (Weinheim) 348 , 463-74, (2015)

Four scaffolds of varied benzylidene derivatives were synthesized and evaluated as Syk inhibitors for the treatment of rheumatoid arthritis (RA). Among these 31 compounds, 3-benzylidene pyrrolidine-2,5-dione derivatives (including 12k) universally showed good...