CKS-17
Modify Date: 2025-08-27 07:55:10
CKS-17 structure
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Common Name | CKS-17 | ||
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| CAS Number | 99273-04-8 | Molecular Weight | 1942.27000 | |
| Density | 1.41±0.1 g/cm3 (20 °C, 760 mmHg) | Boiling Point | N/A | |
| Molecular Formula | C87H148N26O24 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CKS-17CKS-17 is a synthetic retroviral envelope peptide. CKS-17 has the highly conserved amino acid sequences occurring within the transmembrane envelope protein of many animal and human retroviruses. CKS-17 acts as an immunomodulatory epitope and exhibits suppressive properties for numerous immune functions[1][2][3]. |
| Name | L-Leucine, L-leucyl-L-glutaminyl-L-asparaginyl-L-arginyl-L-arginylglycyl-L-leucyl-L-α-aspartyl-L-leucyl-L-leucyl-L-phenylalanyl-L-leucyl-L-lysyl-L-α-glutamylglycylglycyl |
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| Synonym | More Synonyms |
| Description | CKS-17 is a synthetic retroviral envelope peptide. CKS-17 has the highly conserved amino acid sequences occurring within the transmembrane envelope protein of many animal and human retroviruses. CKS-17 acts as an immunomodulatory epitope and exhibits suppressive properties for numerous immune functions[1][2][3]. |
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| Related Catalog | |
| In Vitro | CKS-17 (THP-1 cells) induces increased intracellular cAMP via activation of adenylate cyclase[1]. CKS-17 (15 μM; EL4 cells) inhibits interleukin-2 production by tumor cell products[3]. |
| In Vivo | CKS-17 (10 μM; i.d.; B6AF1 mice and C57BL/6J mice) inhibits delayed-type hypersensitivity (DTH) reactions to sheep erythrocytes in the feet of mice[2]. Animal Model: B6AF1 mice and C57BL/6J mice with DTH models[2] Dosage: 10 μM Administration: Intradermal injection, into the right hind footpad Result: Had a transient depressive effect on DTH reaction. |
| Density | 1.41±0.1 g/cm3 (20 °C, 760 mmHg) |
|---|---|
| Molecular Formula | C87H148N26O24 |
| Molecular Weight | 1942.27000 |
| Exact Mass | 1941.12000 |
| PSA | 839.52000 |
| LogP | 5.14200 |
| InChIKey | RESSROXEVCGJLA-DFNTYYFDSA-N |
| SMILES | CC(C)CC(N)C(=O)NC(CCC(N)=O)C(=O)NC(CC(N)=O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(Cc1ccccc1)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)O)C(=O)NCC(=O)NCC(=O)NC(CC(C)C)C(=O)O |
| 1067: PN: US20090175821 SEQID: 1339 claimed protein |
| CKS-17 |