DDO-02005 free base

Modify Date: 2024-01-09 12:22:47

DDO-02005 free base structure	Common Name	DDO-02005 free base
	CAS Number	1186134-30-4	Molecular Weight	351.44
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₅N₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of DDO-02005 free base

DDO-02005 (free base) is a potent Kv1.5 potassium channel inhibitor with an IC50 value of 0.72 μM. DDO-02005 (free base) has good anti-atrial fibrillation (AF) effect in CaCl2-ACh AF rats model and effective anti-arrhythmic activity caused by aconitine[1].

Name	DDO-02005 free base

Description	DDO-02005 (free base) is a potent Kv1.5 potassium channel inhibitor with an IC50 value of 0.72 μM. DDO-02005 (free base) has good anti-atrial fibrillation (AF) effect in CaCl2-ACh AF rats model and effective anti-arrhythmic activity caused by aconitine[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
Target	IC50: 0.72 μM (Kv1.5 potassium channel)[1]
References	[1]. Zhao L, et al. Design, synthesis, and biological evaluation of arylmethylpiperidines as Kv1.5 potassium channel inhibitors. J Enzyme Inhib Med Chem. 2022;37(1):462-471.

Molecular Formula	C₂₁H₂₅N₃O₂
Molecular Weight	351.44

DDO-02005 free base

Use of DDO-02005 free base

Names

DDO-02005 free base Biological Activity

Chemical & Physical Properties