Dopamine-d5 hydrochloride

Modify Date: 2024-01-05 20:26:20

Dopamine-d5 hydrochloride structure	Common Name	Dopamine-d5 hydrochloride
	CAS Number	2193106-55-5	Molecular Weight	194.67
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₈H₇D₅ClNO₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Dopamine-d5 hydrochloride

Dopamine-d5 hydrochloride is the deuterium labeled Dopamine (hydrochloride). Dopamine hydrochloride (ASL279) is a catecholamine neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain. Dopamine hydrochloride (ASL279) plays several important roles in the brain and body[1]. Dopamine hydrochloride (ASL279) acts through D2 dopamine receptors to induce endocytosis of VEGFR2, which is critical for promoting angiogenesis[1].

Name	Dopamine-d5 hydrochloride

Description	Dopamine-d5 hydrochloride is the deuterium labeled Dopamine (hydrochloride). Dopamine hydrochloride (ASL279) is a catecholamine neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain. Dopamine hydrochloride (ASL279) plays several important roles in the brain and body[1]. Dopamine hydrochloride (ASL279) acts through D2 dopamine receptors to induce endocytosis of VEGFR2, which is critical for promoting angiogenesis[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Ferroptosis Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Juárez Olguín H, et al. The Role of Dopamine and Its Dysfunction as a Consequence of Oxidative Stress. Oxid Med Cell Longev. 2016;2016:9730467. [3]. Basu S, et al. The neurotransmitter dopamine inhibits angiogenesis induced by vascular permeability factor/vascular endothelial growth factor. Nat Med. 2001 May;7(5):569-74.

Molecular Formula	C₈H₇D₅ClNO₂
Molecular Weight	194.67

Dopamine-d5 hydrochloride

Use of Dopamine-d5 hydrochloride

Names

Dopamine-d5 hydrochloride Biological Activity

Chemical & Physical Properties