GSK3-IN-1

Modify Date: 2024-04-08 18:05:48

GSK3-IN-1 Structure
GSK3-IN-1 structure
Common Name GSK3-IN-1
CAS Number 478482-74-5 Molecular Weight 303.767
Density 1.43±0.1 g/cm3(Predicted) Boiling Point 492.2±55.0 °C(Predicted)
Molecular Formula C14H10ClN3OS Melting Point N/A
MSDS N/A Flash Point 251.5±31.5 °C

 Use of GSK3-IN-1


GSK3-IN-1 (compound 11) is a GSK-3 inhibitor with an IC50 value of 12 μM. GSK3-IN-1 can be used in the research of diabetes[1].

 Names

Name 2-chlorobenzyl 5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl sulfide
Synonym More Synonyms

 GSK3-IN-1 Biological Activity

Description GSK3-IN-1 (compound 11) is a GSK-3 inhibitor with an IC50 value of 12 μM. GSK3-IN-1 can be used in the research of diabetes[1].
Related Catalog
Target

GSK-3[1]

References

[1]. Lars Naerum, et al. Scaffold hopping and optimization towards libraries of glycogen synthase kinase-3 inhibitors. Bioorg Med Chem Lett. 2002 Jun 3;12(11):1525-8.

 Chemical & Physical Properties

Density 1.43±0.1 g/cm3(Predicted)
Boiling Point 492.2±55.0 °C(Predicted)
Molecular Formula C14H10ClN3OS
Molecular Weight 303.767
Flash Point 251.5±31.5 °C
Exact Mass 303.023315
LogP 4.10
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.673

 Synonyms

Pyridine, 4-[5-[[(2-chlorophenyl)methyl]thio]-1,3,4-oxadiazol-2-yl]-
MFCD04031734
4-{5-[(2-Chlorobenzyl)sulfanyl]-1,3,4-oxadiazol-2-yl}pyridine