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Quercetin pentaacetate

Quercetin pentaacetate用途

Quercetin pentaacetate 可与 F 蛋白相互作用,结合能低、稳定性好、可阻断病毒粘附。Quercetin pentaacetate 可与RSV 相互作用,抑制病毒在细胞表面粘附。

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Quercetin pentaacetate名称

[ CAS 号 ]:
1064-06-8

[ 英文名 ]:
Quercetin pentaacetate

[英文别名 ]:

Quercetin acetate
penta-O-acetylquercetin
Pentaacetylquercetin
quercetin pentaacetate
3,3',4',5,7-Pentahydroxyflavone pentaacetate
3,3',4',5,7-Pentaacetoxyflavone
FLAVONE,3,3',4',5,7-PENTAHYDROXY-,PENTAACETATE
quercetin peracetate

Quercetin pentaacetate生物活性

[ 描述 ]:

Quercetin pentaacetate 可与 F 蛋白相互作用,结合能低、稳定性好、可阻断病毒粘附。Quercetin pentaacetate 可与RSV 相互作用,抑制病毒在细胞表面粘附。

[ 相关类别 ]:

研究领域 >> 感染

信号通路 >> 抗感染 >> RSV

研究领域 >> 炎症/免疫

[体外研究]

五乙酸槲皮素(0-40μM)对LPS诱导的PGE2生成和COX-2基因表达有明显的抑制作用,对NLA/LPS或L-NAME/LPS共处理的raw264.7细胞有明显的抑制作用[2]。

[参考文献]

[1]. Bruno Rafael Pereira Lopes, et al. Quercetin Pentaacetate Inhibits in Vitro Human Respiratory Syncytial Virus Adhesion. Virus Res. 2020 Jan 15;276:197805.

[2]. Y C Chen, et al. Inhibition of Nitric Oxide Synthase Inhibitors and Lipopolysaccharide Induced Inducible NOS and cyclooxygenase-2 Gene Expressions by Rutin, Quercetin, and Quercetin Pentaacetate in RAW 264.7 Macrophages. J Cell Biochem. 2001;82(4):537-48.

Quercetin pentaacetate物理化学性质

[ 密度 ]:
1.45g/cm3

[ 沸点 ]:
666.4ºC at 760 mmHg

[ 分子式 ]:
C₂₅H₂₀O₁₂

[ 分子量 ]:
512.41900

[ 闪点 ]:
284.7ºC

[ 精确质量 ]:
512.09500

[ PSA ]:
161.71000

[ LogP ]:
3.08650

[ 蒸汽压 ]:
1.27E-17mmHg at 25°C

[ 折射率 ]:
1.6

Quercetin pentaacetate毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LK8985000

CHEMICAL NAME :: Flavone, 3,3',4',5,7-pentahydroxy-, pentaacetate

CAS REGISTRY NUMBER :: 1064-06-8

BEILSTEIN REFERENCE NO. :: 0380215

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C25-H20-O12

MOLECULAR WEIGHT :: 512.45

WISWESSER LINE NOTATION :: T66 BO EVJ CR COV1 DOV1& DOV1 GOV1 IOV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 5 ug/plate

REFERENCE :: SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 197,577,1977

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Quercetin pentaacetate安全信息

[ 海关编码 ]:
2915900090

Quercetin pentaacetate合成路线

详细合成路线

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Quercetin pentaacetate海关

[ 海关编码 ]: 2915900090

[ 中文概述 ]:
2915900090. 其他饱和无环一元羧酸及其酸酐（酰卤、过氧）化物、过氧酸及其卤化、硝化、磺化、亚硝化衍生物. 增值税率:17.0%. 退税率:9.0%. 监管条件:AB(入境货物通关单,出境货物通关单). 最惠国关税:5.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%