Tafenoquine Succinate
Tafenoquine Succinate用途
Tafenoquine Succinate名称
[ CAS 号 ]:
106635-81-8
[ 中文名 ]:
Tafenoquine Succinate
[ 英文名 ]:
Tafenoquine (Succinate)
[英文别名 ]:
- Tafenoquine succinate
- UNII-DL5J0B8VSS
- Tafenoquine Succinate
- tafenoquine maleate
- Etaquine
- Tafenoquine (Succinate)
Tafenoquine Succinate生物活性
[ 描述 ]:
[ 相关类别 ]:
[ 靶点 ]
Anti-malarial[1]
[体内研究]
[参考文献]
[相关活性小分子]
Tafenoquine Succinate物理化学性质
[ 密度 ]:
1.237g/cm3
[ 沸点 ]:
565.6ºC at 760mmHg
[ 分子式 ]:
C28H34F3N3O7
[ 分子量 ]:
581.58100
[ 闪点 ]:
295.9ºC
[ 精确质量 ]:
581.23500
[ PSA ]:
153.23000
[ LogP ]:
6.61990
[ 储存条件 ]:
2-8℃
Tafenoquine SuccinateMSDS
Tafenoquine Succinate毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SA0242400
- CAS REGISTRY NUMBER :
- 106635-81-8
- LAST UPDATED :
- 199107
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C24-H28-F3-N3-O3.C4-H6-O4
- MOLECULAR WEIGHT :
- 581.65
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 416 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 32,1728,1989
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 71 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 32,1728,1989
Tafenoquine Succinate安全信息
[ 危险品运输编码 ]:
NONH for all modes of transport
Tafenoquine Succinate文献
J. Antimicrob. Chemother. 66(11) , 2562-5, (2011)
The present study was designed to elucidate the mechanism of tafenoquine uptake in Leishmania and its sterol dependence.Because tafenoquine is a fluorescent compound, spectrofluorimetric analysis allo...
Transmission-blocking activity of tafenoquine (WR-238605) and artelinic acid against naturally circulating strains of Plasmodium vivax in Thailand.Am. J. Trop. Med. Hyg. 69(5) , 542-7, (2003)
The sporontocidal activity of tafenoquine (WR-238605) and artelinic acid was determined against naturally circulating isolates of Plasmodium vivax in western Thailand. Primaquine was used as a negativ...
Military aviators, special operations forces, and causal malaria prophylaxis.Mil. Med. 168(12) , 1001-6, (2003)
U.S. military aviators are currently restricted to the use of chloroquine or doxycycline for malaria prophylaxis. Ground forces are allowed the additional option of taking mefloquine. These medication...
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价格:
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产品详情:N4-(2,6-二甲氧基-4-甲基-5-(3-(三氟甲基)苯氧基)喹啉-8-基)戊烷-1,4-二胺琥珀酸盐
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联系人:夏言
产品详情:[Perfemiker]Tafenoquine Succinate,≥99%
公司名:武汉壹加壹生物科技有限公司
区域:武汉市江夏区
价格:
¥需询单/1kg
联系人:刘经理
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相关化合物
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