N,N′-亚甲基双丙烯酰胺

N,N′-亚甲基双丙烯酰胺用途

用途一：用作光敏尼龙和光敏塑料原料、建筑灌浆材料，也用于照相、印刷、制版等
用途二：可在油田钻井作业中和建筑灌浆作业中用作堵水剂，亦可在丙烯酸树脂和粘合剂合成中用作交联剂
用途三：用作分离氨基酸的重要材料及光敏尼龙或光敏塑料的重要原料
用途四：生物高分子化合物(蛋白质、多肽、核酸)的分离。制备聚丙烯酰胺凝胶的交联剂。聚丙烯酰胺凝胶技术和临床检验。

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N,N′-亚甲基双丙烯酰胺名称

[ CAS 号 ]:
110-26-9

[ 中文名 ]:
N,N'-亚甲基双丙烯酰胺

[ 英文名 ]:
N,N′-Methylenebisacrylamide

[中文别名 ]:

[英文别名 ]:

Methylene bisacrylamide
N,N′-Methylenebisacrylamide
N,N′-methylenediacrylamide
N,N'-Methylenebisacrylamide
N,N‘-Methylenebisacrylamide
N,N-Methylenebisacrylamide
EINECS 203-750-9
N,N'-Methylenediacrylamide
N,N'-Methylenebis(2-propenamide)
MFCD00008625

N,N′-亚甲基双丙烯酰胺生物活性

[ 描述 ]:

N、 N’-亚甲基双丙烯酰胺是一种生物化学试剂,可作为生物材料或有机化合物进行生命科学相关研究。

[ 相关类别 ]:

研究领域 >> 其他

N,N′-亚甲基双丙烯酰胺物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
445.1±41.0 °C at 760 mmHg

[ 熔点 ]:
>300 °C(lit.)

[ 分子式 ]:
C₇H₁₀N₂O₂

[ 分子量 ]:
154.167

[ 闪点 ]:
215.0±27.8 °C

[ 精确质量 ]:
154.074234

[ PSA ]:
58.20000

[ LogP ]:
-1.44

[ 外观性状 ]:
白色结晶粉末

[ 蒸汽密度 ]:
5.31 (vs air)

[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C

[ 折射率 ]:
1.475

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
0.01-0.1 g/100 mL at 18 ºC

N,N′-亚甲基双丙烯酰胺MSDS

N,N′-亚甲基双丙烯酰胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AS3678000

CHEMICAL NAME :: Acrylamide, N,N'-methylenebis-

CAS REGISTRY NUMBER :: 110-26-9

BEILSTEIN REFERENCE NO. :: 1706297

LAST UPDATED :: 199710

DATA ITEMS CITED :: 18

MOLECULAR FORMULA :: C7-H10-N2-O2

MOLECULAR WEIGHT :: 154.19

WISWESSER LINE NOTATION :: 1U1VM1MV1U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 390 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - tremor Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :: LC - Lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >41 ppm/6H

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - acute pulmonary edema

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 380 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LC - Lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >41 ppm/6H

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - acute pulmonary edema

TYPE OF TEST :: LC - Lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: >41 ppm/6H

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - acute pulmonary edema

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3206 mg/kg/8W-I

TOXIC EFFECTS :: Blood - changes in erythrocyte (RBC) count Blood - changes in leukocyte (WBC) count Related to Chronic Data - changes in testicular weight

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 3208 mg/kg

SEX/DURATION :: male 16 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - testes, epididymis, sperm duct

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 360 mg/kg

SEX/DURATION :: female 6-17 day(s) after conception

TOXIC EFFECTS :: Reproductive - Maternal Effects - parturition Reproductive - Maternal Effects - other effects Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 50 mg/kg

SEX/DURATION :: male 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 225 mg/kg

SEX/DURATION :: male 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TYPE OF TEST :: Dominant lethal test

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 450 mg/kg/5D (Continuous)

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 229,161,1990 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83963 No. of Facilities: 199 (estimated) No. of Industries: 4 No. of Occupations: 5 No. of Employees: 2098 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83963 No. of Facilities: 10 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 66 (estimated) No. of Female Employees: 35 (estimated)

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N,N′-亚甲基双丙烯酰胺安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H332

[ 个人防护装备 ]:
Eyeshields;Faceshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R20/21/22

[ 安全声明 (欧洲) ]:
S22-S36/37

[ 危险品运输编码 ]:
UN 2811

[ WGK德国 ]:
2

[ RTECS号 ]:
AS3678000

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1(b)

[ 海关编码 ]:
2924199090

N,N′-亚甲基双丙烯酰胺合成路线

N,N′-亚甲基双丙烯酰胺上下游产品

N,N′-亚甲基双丙烯酰胺上游产品

N,N′-亚甲基双丙烯酰胺下游产品

N,N′-亚甲基双丙烯酰胺制备

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N,N′-亚甲基双丙烯酰胺海关

[ 海关编码 ]: 2924199090

[ 中文概述 ]:
2924199090. 其他无环酰胺（包括无环氨基甲酸酯)(包括其衍生物及盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

N,N′-亚甲基双丙烯酰胺文献

Matrix stiffening and β1 integrin drive subtype-specific fibroblast accumulation in lung cancer.

Mol. Cancer Res. 13(1) , 161-73, (2015)

The crucial role of tumor-associated fibroblasts (TAF) in cancer progression is now clear in non-small cell lung cancer (NSCLC). However, therapies against TAFs are limited due to a lack of understand...

Effects of pentylenetetrazole kindling on mitogen-activated protein kinases levels in neocortex and hippocampus of mice.

Neurochem. Res. 39(12) , 2492-500, (2014)

The epileptogenesis process involves cell signaling events associated with neuroplasticity. The mitogen-activated protein kinases (MAPKs) integrate signals originating from a variety of extracellular ...

Peripheral Blood-Derived Mesenchymal Stromal Cells Promote Angiogenesis via Paracrine Stimulation of Vascular Endothelial Growth Factor Secretion in the Equine Model.

Stem Cells Transl. Med. 3(12) , 1514-25, (2014)

Mesenchymal stromal cells (MSCs) have received much attention as a potential treatment of ischemic diseases, including ischemic tissue injury and cardiac failure. The beneficial effects of MSCs are th...

更多文献

N,N′-亚甲基双丙烯酰胺

N,N′-亚甲基双丙烯酰胺用途

N,N′-亚甲基双丙烯酰胺名称

N,N′-亚甲基双丙烯酰胺生物活性

N,N′-亚甲基双丙烯酰胺物理化学性质

N,N′-亚甲基双丙烯酰胺MSDS

详细MSDS(安全技术说明书)

N,N′-亚甲基双丙烯酰胺毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

N,N′-亚甲基双丙烯酰胺安全信息

N,N′-亚甲基双丙烯酰胺合成路线

详细合成路线

N,N′-亚甲基双丙烯酰胺上下游产品

N,N′-亚甲基双丙烯酰胺上游产品

N,N′-亚甲基双丙烯酰胺下游产品

N,N′-亚甲基双丙烯酰胺制备

N,N′-亚甲基双丙烯酰胺海关

N,N′-亚甲基双丙烯酰胺文献

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