二乙醇胺_MSDS_用途_密度_二乙醇胺CAS号【111-42-2】

用途一：亚氨基二乙醇又称二乙醇胺，是除草剂草甘膦的中间体。
用途二：用作气体的净化剂，也用作合成药物及有机合成的原料
用途三：用作分析试剂、气相色谱固定液、软化剂及润滑剂，也用于有机合成
用途四：二乙醇胺主要用作CO2、H2S和SO2等酸性气体吸收剂、非离子表面活性剂、乳化剂、擦光剂、工业气体净化剂、润滑剂。在洗发剂和轻型去垢剂内用作增稠剂泡沫改进剂，在合成纤维和皮革生产中用作柔软剂。二乙醇胺与70%硫酸作用，脱水环化生成吗啉（即1,4-氧氮杂环己烷）。吗啉和二乙醇胺都是有机合成的中间体，例如可用来生产纺织工业中某些光学漂白剂，吗啉的脂肪酸盐可用作防腐剂，吗啉还可用来生产中枢抑制药福尔可定或作为溶剂。二乙醇胺在分析化学上用作试剂和气相色谱固定液，可选择性地保留和分离醇、二醇、胺、吡啶、喹啉、哌嗪、硫醇、硫醚和水。

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[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
268.4±0.0 °C at 760 mmHg

[ 熔点 ]:
28 °C(lit.)

[ 分子式 ]:
C₄H₁₁NO₂

[ 分子量 ]:
105.136

[ 闪点 ]:
137.8±0.0 °C

[ 精确质量 ]:
105.078979

[ PSA ]:
52.49000

[ LogP ]:
-1.50

[ 外观性状 ]:
固体或粘性液体带有一种胺的气味

[ 蒸汽密度 ]:
3.6 (vs air)

[ 蒸汽压 ]:
0.0±1.2 mmHg at 25°C

[ 折射率 ]:
1.466

[ 储存条件 ]:
库房通风低温干燥,与酸类分开存放

[ 稳定性 ]:
Stable. Incompatible with carbon dioxide, strong acids, strong oxidizing agents. Deliquescent.

[ 水溶解性 ]:
混溶

详细MSDS(安全技术说明书)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KL2975000

CHEMICAL NAME :: Ethanol, 2,2'-iminodi-

CAS REGISTRY NUMBER :: 111-42-2

BEILSTEIN REFERENCE NO. :: 0605315

LAST UPDATED :: 199712

DATA ITEMS CITED :: 49

MOLECULAR FORMULA :: C4-H11-N-O2

MOLECULAR WEIGHT :: 105.16

WISWESSER LINE NOTATION :: Q2M2Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 12/29/1971

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,685,1986

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- Volume(issue)/page/year: 29,1363,1946

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,685,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 620 uL/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Behavioral - tremor Skin and Appendages - hair

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0516797

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 120 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EVSSAV Environmental Space Science. English Translation of Kosmicheskaya Biologiya Meditsina. 1967-70. Volume(issue)/page/year: 2,289,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EVSSAV Environmental Space Science. English Translation of Kosmicheskaya Biologiya Meditsina. 1967-70. Volume(issue)/page/year: 2,289,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 778 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EVSSAV Environmental Space Science. English Translation of Kosmicheskaya Biologiya Meditsina. 1967-70. Volume(issue)/page/year: 2,289,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EVSSAV Environmental Space Science. English Translation of Kosmicheskaya Biologiya Meditsina. 1967-70. Volume(issue)/page/year: 2,289,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3300 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - excitement Behavioral - muscle contraction or spasticity

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 29(11),25,1964

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 210 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0516742

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 2200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EVSSAV Environmental Space Science. English Translation of Kosmicheskaya Biologiya Meditsina. 1967-70. Volume(issue)/page/year: 2,289,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 7640 uL/kg

TOXIC EFFECTS :: Behavioral - ataxia Musculoskeletal - other changes Skin and Appendages - dermatitis, other (after systemic exposure)

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0516797

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85INA8 "Documentation of the Threshold Limit Values and Biological Exposure Indices," 5th ed., Cincinnati, OH, American Conference of Governmental Industrial Hygienists, Inc., 1986 Volume(issue)/page/year: 5,197,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 11900 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0516742

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0520710 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 52 gm/kg/14D-C

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes in urine composition Blood - normocytic anemia Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NIH-92-3343

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8827 mg/kg/13W-C

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in bladder weight Blood - normocytic anemia Related to Chronic Data - changes in testicular weight

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NIH-92-3343

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 49 gm/kg/7W-C

TOXIC EFFECTS :: Liver - other changes Blood - normocytic anemia Related to Chronic Data - death

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 17,308,1970

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1008 mg/kg/16D-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes in urine composition Blood - normocytic anemia Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NIH-92-3343

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8125 mg/kg/13W-I

TOXIC EFFECTS :: Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Blood - normocytic anemia

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NIH-92-3343

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 30366 mg/kg/14D-C

TOXIC EFFECTS :: Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NIH-92-3343

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 38402 mg/kg/13W-C

TOXIC EFFECTS :: Cardiac - changes in heart weight Kidney, Ureter, Bladder - changes in bladder weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NIH-92-3343

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 30 gm/kg/16D-I

TOXIC EFFECTS :: Liver - changes in liver weight Skin and Appendages - dermatitis, other (after systemic exposure) Related to Chronic Data - death

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NIH-92-3343

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 40950 mg/kg/13W-I

TOXIC EFFECTS :: Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NIH-92-3343 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 18382 mg/kg

SEX/DURATION :: male 14 day(s) pre-mating

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NIH-92-3343 *** REVIEWS *** ACGIH TLV-TWA 2 mg/m3 (0.46 ppm) (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 3 ppm (15 mg/m3) JAN 1993 OEL-BELGIUM:TWA 3 ppm (13 mg/m3) JAN 1993 OEL-DENMARK:TWA 3 ppm (15 mg/m3) JAN 1993 OEL-FRANCE:TWA 3 ppm (15 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 3 ppm (15 mg/m3) JAN 1993 OEL-RUSSIA:STEL 5 mg/m3;Skin JAN 1993 OEL-SWITZERLAND:TWA 0.1 mg/m3 JAN 1993 OEL-SWITZERLAND:TWA 3 ppm (13 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 3 ppm (15 mg/m3) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO DIETHANOLAMINE-air:10H TWA 3 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0517 No. of Facilities: 315 (estimated) No. of Industries: 3 No. of Occupations: 2 No. of Employees: 857 (estimated) NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 24615 No. of Facilities: 18443 (estimated) No. of Industries: 147 No. of Occupations: 118 No. of Employees: 186455 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 24615 No. of Facilities: 46466 (estimated) No. of Industries: 249 No. of Occupations: 171 No. of Employees: 828471 (estimated) No. of Female Employees: 218923 (estimated)

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[ 符号 ]:

GHS05, GHS07, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302-H315-H318-H373-H412

[ 警示性声明 ]:
P260-P280-P301 + P312 + P330-P305 + P351 + P338 + P310

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R22;R38;R41;R48/22

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S46

[ 危险品运输编码 ]:
3267

[ WGK德国 ]:
1

[ RTECS号 ]:
KL2975000

[ 包装等级 ]:
II

[ 海关编码 ]:
2922120090

详细合成路线

二乙醇胺上游产品

二乙醇胺下游产品

1.由环氧乙烷与氨反应得到二乙醇胺，同时也得到一乙醇胺和三乙醇胺。将环氧乙烷；氨水送入反应器中，在反应温度30-40℃，反应压力70.9-304kPa下，进行缩合反应生成一；二；三乙醇胺混合液，在90-120℃下经脱水浓缩后，送入三个减压精馏塔进行减压蒸馏，按不同沸点截取馏分，则可得纯度达99%的一乙醇胺；二乙醇胺和三乙醇胺成品。在反应过程中，如加大环氧乙烷比例，则二；三乙醇胺生成比例增大，可提高二；三乙醇胺的收率。

精制方法：工业制品中含有2%以下的乙醇胺、三乙醇胺和1.5%以下的水分。精制时先进行减压蒸馏，再用水蒸气蒸馏除去乙醇胺。三乙醇胺可在其水溶液中加入氢氧化钠使成碱金属盐析出除去。最后再进行减压蒸馏精制。操作中注意防止吸收二氧化碳。

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[ 海关编码 ]: 2922120001

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装, 原产地证据文件及编号(例附原产地证书, 原产于美国、日本、伊朗、马来西亚、台湾、墨西哥的

[ Summary ]:
2922120001 2,2'-azanediyldiethanol。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%

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公司名：上海化源世纪贸易有限公司

区域：上海市普陀区

价格：

联系人：徐经理

产品详情：二乙醇胺

公司名：上海吉至生化科技有限公司

区域：上海市奉贤区

价格：
￥58.0/500ml

联系人：刘佳

产品详情：二乙醇胺

公司名：上海源溪生物科技有限公司

区域：上海市浦东新区

价格：
￥需询单/1g

联系人：赖经理

产品详情：Diolamine

公司名：上海阿拉丁生化科技股份有限公司

区域：上海市浦东新区

价格：
￥需询单/1mg ￥需询单/1g ￥需询单/1g ￥需询单/1g

联系人：阿拉丁

产品详情：二乙醇胺

公司名：中山市迪欣化工有限公司

区域：中山市三角镇

价格：
￥26.0/200kg

联系人：陈雪萍

产品详情：二乙醇胺

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