2,4-二氯苯酚
2,4-二氯苯酚用途
用作农药、医药中间体，用于合成除草醚、2,4-D等产品
【用途二】
用于有机合成
【用途三】
2，4-二氯苯酚主要用作农药和医药中间体。在农药上可合成有机磷杀虫剂丙硫磷、除草剂2，4-滴、2，4-滴丁酯、禾草灵、甲羧除草醚、甲氧除草醚、唑啶草酮(azafenidin)、丙炔恶草酮(oxadiargyl)以及新杀菌剂氰菌胺(fenoxanil)等。医药方面可作为药物硫双二氯酚的重要原料。
【用途四】
用作农药和医药中间体。用于合成除草醚、2,4-D、伊比磷（EPBP）、毒克散、格螨酯以及药物硫双二氯酚。
【用途五】
生化研究。有机合成。气相色谱对比样品。植物生长促进剂。
【用途六】
用于有机合成。校准仪器和装置；评价方法；工作标准；质量保证/质量控制；其他。
2,4-二氯苯酚名称
[ CAS 号 ]:
120-83-2
[ 中文名 ]:
2.4二氯酚
[ 英文名 ]:
2,4-Dichlorophenol
[中文别名 ]:
[英文别名 ]:
- 2,4-DCP
- 2,4-di-chlorophenol
- Isobac
- rcrawastenumberu081
- EINECS 204-429-6
- 2,4-dlchlorophenol
- DL-2,4,6-Trifluoro-Phe-OH
- Phenol, 2,4-dichloro-
- 1,3-Dichloro-4-hydroxybenzene
- 2,4,6-TRIFLUORO-DL-PHENYLALANINE
2,4-二氯苯酚物理化学性质
[ 密度 ]:
1.5±0.1 g/cm3
[ 沸点 ]:
210.0±0.0 °C at 760 mmHg
[ 熔点 ]:
42-43 °C(lit.)
[ 分子式 ]:
C6H4Cl2O
[ 分子量 ]:
163.001
[ 闪点 ]:
113.9±0.0 °C
[ 精确质量 ]:
161.963913
[ PSA ]:
20.23000
[ LogP ]:
2.99
[ 外观性状 ]:
白色至灰白色结晶固体
[ 蒸汽压 ]:
0.1±0.4 mmHg at 25°C
[ 折射率 ]:
1.594
[ 储存条件 ]:
库房通风低温干燥,与氧化剂、食品化工添加剂、酸类分开存放
[ 水溶解性 ]:
4.5 g/L (20 ºC)
2,4-二氯苯酚MSDS
2,4-二氯苯酚毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SK8575000
- CHEMICAL NAME :
- Phenol, 2,4-dichloro-
- CAS REGISTRY NUMBER :
- 120-83-2
- BEILSTEIN REFERENCE NO. :
- 0742467
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 34
- MOLECULAR FORMULA :
- C6-H4-Cl2-O
- MOLECULAR WEIGHT :
- 163.00
- WISWESSER LINE NOTATION :
- QR BG DG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 47 mg/kg
- TOXIC EFFECTS :
- Behavioral - food intake (animal) Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - other changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 430 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Nutritional and Gross Metabolic - body temperature increase
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1730 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1276 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 153 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 3160 mg/kg
- TOXIC EFFECTS :
- Behavioral - food intake (animal) Lungs, Thorax, or Respiration - pulmonary emboli Liver - other changes
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 464 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 790 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 91 gm/kg/13W-C
- TOXIC EFFECTS :
- Blood - changes in bone marrow (not otherwise specified)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 31770 mg/kg/90D-C
- TOXIC EFFECTS :
- Behavioral - fluid intake Blood - changes in cell count (unspecified) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 437 gm/kg/13W-C
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 67200 mg/kg/14D-C
- TOXIC EFFECTS :
- Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 16 gm/kg/39W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 20 mg/kg
- SEX/DURATION :
- female 1-20 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 7500 mg/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 7500 mg/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 666 mg/kg
- SEX/DURATION :
- female 6-14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
MUTATION DATA
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 500 umol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 182,135,1987 *** REVIEWS *** IARC Cancer Review:Human Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 41,319,1986 TOXICOLOGY REVIEW STEVA8 Science of the Total Environment. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1972- Volume(issue)/page/year: 2,305,1974 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4154 No. of Facilities: 6 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 63 (estimated) No. of Female Employees: 23 (estimated)
2,4-二氯苯酚安全信息
[ 符号 ]:
GHS05, GHS06, GHS09
[ 信号词 ]:
Danger
[ 危害声明 ]:
H300-H302-H311-H314-H411
[ 警示性声明 ]:
P264-P273-P280-P301 + P310-P305 + P351 + P338-P310
[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P2 (EN 143) respirator cartridges;type P3 (EN 143) respirator cartridges
[ 危害码 (欧洲) ]:
T:Toxic
[ 风险声明 (欧洲) ]:
R22;R24;R34;R51/53
[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45-S61-S36/37-S16
[ 危险品运输编码 ]:
UN 2928 6.1/PG 2
[ WGK德国 ]:
3
[ RTECS号 ]:
SK8575000
[ 包装等级 ]:
III
[ 危险类别 ]:
6.1
[ 海关编码 ]:
29081000
2,4-二氯苯酚合成路线
2,4-二氯苯酚上下游产品
2,4-二氯苯酚上游产品
2,4-二氯苯酚下游产品
2,4-二氯苯酚制备
采用苯酚催化氯化法生产2,4-二氯苯酚。将熔融的苯酚抽入氯化罐和吸收罐，加热到50~60ºC，通入氯气，氯气先进入氯化罐，再串联进入吸收罐，尾气通入石墨薄膜吸收塔，用水吸收尾气中的氯化氢。反应罐的夹套及盘管道冷却水移出反应热。当氯化罐物料的相对密度达到1.402~1.405（40ºC）时为氯化终点，停止通氯气，从氯化罐放出2,4-二氯苯酚。下一批氯化时，原吸收罐作为氯化罐，先通入新鲜氯气，而原氯化罐抽入原料苯酚作为吸收罐使用。
2,4-二氯苯酚海关
[ 海关编码 ]: 2908199090
[ 中文概述 ]:
HS:2908199090 其他酚及酚醇的仅含卤素取代基的衍生物及其盐 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:5.5% 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0%
2,4-二氯苯酚文献
Eur. J. Pharm. Sci. 63 , 14-21, (2014)
A capillary isoelectric focusing (cIEF) method was developed for the determination of the ionization constants (pKa) of small molecules. Two approaches used to decrease the electroosmotic flow (EOF) w...
Efficiency of biological activator formulated material (BAFM) for volatile organic compounds removal--preliminary batch culture tests with activated sludge.Environ. Technol. 33(13-15) , 1671-6, (2012)
During biological degradation, such as biofiltration of air loaded with volatile organic compounds, the pollutant is passed through a bed packed with a solid medium acting as a biofilm support. To imp...
Preparation and evaluation of poly(alkyl methacrylate-co-methacrylic acid-co-ethylene dimethacrylate) monolithic columns for separating polar small molecules by capillary liquid chromatography.Anal. Chim. Acta 871 , 57-65, (2015)
In this study, methacrylic acid (MAA) was incorporated with alkyl methacrylates to increase the hydrophilicity of the synthesized ethylene dimethacrylate-based (EDMA-based) monoliths for separating po...
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公司名：上海化源世纪贸易有限公司
区域：上海市普陀区
价格：
联系人：徐经理
产品详情：2,4-二氯酚标准溶液
公司名：上海吉至生化科技有限公司
区域：上海市奉贤区
价格：
￥178.0/500g
联系人：刘佳
产品详情：2,4-二氯苯酚
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥75.0/5g
￥需询单/1g
￥需询单/1g
￥需询单/1g
联系人：阿拉丁
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相关化合物
【2,4-二氯苯酚】化源网提供2,4-二氯苯酚CAS号120-83-2，2,4-二氯苯酚MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询2,4-二氯苯酚上化源网，专业又轻松。>>电脑版：2,4-二氯苯酚
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