< 生产厂家价格 >

2-(4-异丁基苯基)(3,3,3-2H3)丙酸

2-(4-异丁基苯基)(3,3,3-2H3)丙酸用途

Ibuprofen D3 是一种 Ibuprofen 氘代物。Ibuprofen 是 COX-1 和 COX-2 的抑制剂,IC50 分别为 13 μM 和 370 μM。

点击显示

2-(4-异丁基苯基)(3,3,3-2H3)丙酸名称

[ CAS 号 ]:
121662-14-4

[ 中文名 ]:
布洛芬-d3

[ 英文名 ]:
2-(4-Isobutylphenyl)(3,3,3-2H3)propanoic acid

[英文别名 ]:

Ibuprofen-d3
2-(4-Isobutylphenyl)(3,3,3-H)propanoic acid
rac Ibuprofen-d3

2-(4-异丁基苯基)(3,3,3-2H3)丙酸生物活性

[ 描述 ]:

Ibuprofen D3 是一种 Ibuprofen 氘代物。Ibuprofen 是 COX-1 和 COX-2 的抑制剂,IC50 分别为 13 μM 和 370 μM。

[ 相关类别 ]:

研究领域 >> 炎症/免疫

信号通路 >> 免疫及炎症 >> COX

[参考文献]

[1]. Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7.

2-(4-异丁基苯基)(3,3,3-2H3)丙酸物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
319.6±11.0 °C at 760 mmHg

[ 熔点 ]:
69-71ºC

[ 分子式 ]:
C₁₃H₁₅D₃O₂

[ 分子量 ]:
209.299

[ 闪点 ]:
216.7±14.4 °C

[ 精确质量 ]:
209.149506

[ PSA ]:
37.30000

[ LogP ]:
3.72

[ 外观性状 ]:
固体

[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C

[ 折射率 ]:
1.519

[ 储存条件 ]:
-20°C Freezer

2-(4-异丁基苯基)(3,3,3-2H3)丙酸MSDS

详细MSDS(安全技术说明书)

2-(4-异丁基苯基)(3,3,3-2H3)丙酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn,N

[ 风险声明 (欧洲) ]:
22-51/53

[ 安全声明 (欧洲) ]:
61

[ 危险品运输编码 ]:
UN3077 9/PG 3

2-(4-异丁基苯基)(3,3,3-2H3)丙酸文献

Determination of selected pharmaceuticals in tap water and drinking water treatment plant by high-performance liquid chromatography-triple quadrupole mass spectrometer in Beijing, China.

Environ. Sci. Pollut. Res. Int. 22(3) , 1854-67, (2015)

A simultaneous determination method of 14 multi-class pharmaceuticals using solid-phase extraction (SPE) followed by high-performance liquid chromatography-tandem mass spectrometer (HPLC-MS/MS) was es...

Development of a SPE-UHPLC-MS/MS methodology for the determination of non-steroidal anti-inflammatory and analgesic pharmaceuticals in seawater.

J. Pharm. Biomed. Anal. 106 , 61-70, (2015)

An analytical methodology for the simultaneous determination of seven pharmaceuticals and two metabolites belonging to the non-steroidal anti-inflammatory drugs (NSAIDs) and analgesics therapeutic gro...

Rapid analysis of pharmaceuticals and personal care products in fish plasma micro-aliquots using liquid chromatography tandem mass spectrometry.

J. Chromatogr. A. 1383 , 104-11, (2015)

A sensitive analytical method based on liquid-liquid extraction (LLE) and liquid chromatography tandem mass spectrometry (LC-MS/MS) was developed for rapid analysis of 11 pharmaceuticals and personal ...

更多文献