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盐酸伐昔洛韦

盐酸伐昔洛韦用途

Valacyclovir盐酸盐是抗HSV化合物。

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盐酸伐昔洛韦名称

[ CAS 号 ]:
124832-27-5

[ 中文名 ]:
盐酸伐昔洛韦水合物

[ 英文名 ]:
Valacyclovir hydrochloride

[中文别名 ]:

[英文别名 ]:

MFCD01861507
Valaciclovir
Valacyclovir hydrochloride
Zelitrex
Valaciclovir hydrochloride
Valaciclovir HCl
256u
Valacyclovir hydrochloride hydrate
Valacyclovir (hydrochloride)

盐酸伐昔洛韦生物活性

[ 描述 ]:

Valacyclovir盐酸盐是抗HSV化合物。

[ 相关类别 ]:

信号通路 >> 抗感染 >> HSV

研究领域 >> 感染

[参考文献]

[1]. Valacyclovir. New indication: for genital herpes, simpler administration. Can Fam Physician. 1999 Jul;45:1698-700, 1703-5.

[2]. Lycke J, et al. Acyclovir levels in serum and cerebrospinal fluid after oral administration of valacyclovir. Antimicrob Agents Chemother. 2003 Aug;47(8):2438-41.

[3]. Comparison of efficacies of famciclovir and valaciclovir against herpes simplex virus type 1 in a murineimmunosuppression model. Antimicrob Agents Chemother. 1995 May;39(5):1114-9.

[4]. Dhaliwal DK, Romanowski EG, Yates KA, Valacyclovir inhibits recovery of ocular HSV-1 after experimental reactivation by excimer laser keratectomy. Cornea. 1999 Nov;18(6):693-9.

[5]. Guo A, Hu P, Balimane PV, Interactions of a nonpeptidic drug, valacyclovir, with the human intestinal peptide transporter (hPEPT1) expressed in a mammalian cell line.J Pharmacol Exp Ther. 1999 Apr;289(1):448-54.

[相关活性小分子]

盐酸伐昔洛韦物理化学性质

[ 密度 ]:
1.55g/cm3

[ 沸点 ]:
588.4ºC at 760 mmHg

[ 熔点 ]:
170-172ºC

[ 分子式 ]:
C₁₃H₂₁ClN₆O₄

[ 分子量 ]:
360.797

[ 闪点 ]:
309.7ºC

[ 精确质量 ]:
360.131287

[ PSA ]:
151.14000

[ LogP ]:
1.28590

[ 外观性状 ]:
白色至灰白色结晶粉末

[ 蒸汽压 ]:
7.95E-14mmHg at 25°C

[ 折射率 ]:
1.673

[ 储存条件 ]:
Refrigerator

[ 水溶解性 ]:
水溶性：可溶

盐酸伐昔洛韦MSDS

盐酸伐昔洛韦安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 警示性声明 ]:
P301 + P312 + P330

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
26-36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2933990090

盐酸伐昔洛韦合成路线

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盐酸伐昔洛韦海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

盐酸伐昔洛韦文献

Oral antiviral therapy for prevention of genital herpes outbreaks in immunocompetent and nonpregnant patients.

Cochrane Database Syst. Rev. 8 , CD009036, (2014)

Genital herpes is caused by herpes simplex virus 1 (HSV-1) or 2 (HSV-2). Some infected people experience outbreaks of genital herpes, typically, characterized by vesicular and erosive localized painfu...

Acute retinal necrosis associated with Epstein-Barr virus: immunohistopathologic confirmation.

JAMA Ophthalmol. 132(7) , 881-2, (2014)

Acute retinal necrosis (ARN) is an infectious retinitis primarily caused by the herpesviruses. Although the Epstein-Barr virus (EBV) has been implicated as a cause of ARN, to our knowledge, there has ...

A pilot study examining the safety and tolerability of valacyclovir in veterans with hepatitis C virus/herpes simplex virus type 2 coinfection.

Am. J. Med. Sci. 348(6) , 455-9, (2014)

We performed a pilot study examining the safety and tolerability of valacyclovir in veterans with herpes simplex virus type 2 and hepatitis C virus (HCV) coinfection.We performed a randomized double-b...

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盐酸伐昔洛韦

盐酸伐昔洛韦用途

盐酸伐昔洛韦名称

盐酸伐昔洛韦生物活性

盐酸伐昔洛韦物理化学性质

盐酸伐昔洛韦MSDS

详细MSDS(安全技术说明书)

盐酸伐昔洛韦安全信息

盐酸伐昔洛韦合成路线

详细合成路线

盐酸伐昔洛韦上下游产品

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盐酸伐昔洛韦文献

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