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头孢克肟三水合物

头孢克肟三水合物用途

Cefixime trihydrate (FR-17027 trihydrate) 是第三代头孢菌素类抗生素, 用于研究一些细菌感染。

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头孢克肟三水合物名称

[ CAS 号 ]:
125110-14-7

[ 中文名 ]:
头孢克肟三水合物

[ 英文名 ]:
Cefixime trihydrate

[英文别名 ]:

CEFIXIME TRIHYDRATE

头孢克肟三水合物生物活性

[ 描述 ]:

Cefixime trihydrate (FR-17027 trihydrate) 是第三代头孢菌素类抗生素, 用于研究一些细菌感染。

[ 相关类别 ]:

研究领域 >> 感染

研究领域 >> 炎症/免疫

信号通路 >> 抗感染 >> 细菌

[参考文献]

[1]. Neu HC, et al. In vitro activity of a new broad spectrum, beta-lactamase-stable oral cephalosporin, cefixime. Pediatr Infect Dis J. 1987 Oct;6(10):958-62.

[2]. Unemo M, et al. High-level cefixime- and ceftriaxone-resistant Neisseria gonorrhoeae in France: novel penA mosaic allele in a successful international clone causes treatment failure. Antimicrob Agents Chemother. 2012 Mar;56(3):1273-80.

头孢克肟三水合物物理化学性质

[ 熔点 ]:
218-225℃

[ 分子式 ]:
C₁₆H₂₁N₅O₁₀S₂

[ 分子量 ]:
507.495

[ 精确质量 ]:
507.072968

[ PSA ]:
265.74000

[ LogP ]:
0.17230

[ 储存条件 ]:
2-8°C，干燥，密封

头孢克肟三水合物MSDS

详细MSDS(安全技术说明书)

头孢克肟三水合物安全信息

[ 符号 ]:

GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H317-H334

[ 警示性声明 ]:
P261-P280-P342 + P311

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
R42/43

[ 安全声明 (欧洲) ]:
S22

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

头孢克肟三水合物文献

In vitro antibacterial activity of AZD0914, a new spiropyrimidinetrione DNA gyrase/topoisomerase inhibitor with potent activity against Gram-positive, fastidious Gram-Negative, and atypical bacteria.

Antimicrob. Agents Chemother. 59(1) , 467-74, (2014)

AZD0914 is a new spiropyrimidinetrione bacterial DNA gyrase/topoisomerase inhibitor with potent in vitro antibacterial activity against key Gram-positive (Staphylococcus aureus, Staphylococcus epiderm...

Characterization of urinary tract infection-associated Shiga toxin-producing Escherichia coli.

Infect. Immun. 82(11) , 4631-42, (2014)

Enterohemorrhagic Escherichia coli (EHEC), a subgroup of Shiga toxin (Stx)-producing E. coli (STEC), is a leading cause of diarrhea and hemolytic-uremic syndrome (HUS) in humans. However, urinary trac...

The characterization and antibiotic resistance profiles of clinical Escherichia coli O25b-B2-ST131 isolates in Kuwait.

BMC Microbiol. 14 , 214, (2014)

Escherichia coli O25b-B2-ST131 are considered virulent extra-intestinal pathogens causing serious clinical complications such as urinary tract infection and bacteraemia. Our main objectives in this st...

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