磺胺林
磺胺林用途
磺胺林名称
[ CAS 号 ]:
152-47-6
[ 中文名 ]:
磺胺林
[ 英文名 ]:
sulfalene
[中文别名 ]:
[英文别名 ]:
- Sulfamethopyrazine
- sulfalene
- EINECS 205-804-7
- N-(3-Methoxypyrazin-2-yl)sulfanilamide
- SMP
- MFCD00437754
- N1-(3-Methoxy-2-pyrazinyl)sulfanilamide
磺胺林生物活性
[ 描述 ]:
[ 相关类别 ]:
[ 靶点 ]
Parasite[1]
[参考文献]
[相关活性小分子]
磺胺林物理化学性质
[ 密度 ]:
1.5±0.1 g/cm3
[ 沸点 ]:
488.6±55.0 °C at 760 mmHg
[ 熔点 ]:
270 °C (dec.)(lit.)
[ 分子式 ]:
C11H12N4O3S
[ 分子量 ]:
280.303
[ 闪点 ]:
249.3±31.5 °C
[ 精确质量 ]:
280.063019
[ PSA ]:
115.58000
[ LogP ]:
1.10
[ 外观性状 ]:
白色或略黄色晶体粉末
[ 蒸汽压 ]:
0.0±1.2 mmHg at 25°C
[ 折射率 ]:
1.647
[ 储存条件 ]:
室温
[ 水溶解性 ]:
微溶：甲醇
磺胺林MSDS
磺胺林毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WP0175000
- CHEMICAL NAME :
- Sulfanilamide, N(sup 1)-(3-methoxypyrazinyl)-
- CAS REGISTRY NUMBER :
- 152-47-6
- BEILSTEIN REFERENCE NO. :
- 0622512
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 17
- MOLECULAR FORMULA :
- C11-H12-N4-O3-S
- MOLECULAR WEIGHT :
- 280.33
- WISWESSER LINE NOTATION :
- T6N DNJ BO1 CMSWR DZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2739 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2120 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1790 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1292 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1590 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 893 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 132 mg/kg
- TOXIC EFFECTS :
- Vascular - BP lowering not characterized in autonomic section
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 46 gm/kg/33W-C
- TOXIC EFFECTS :
- Endocrine - thyroid weight (goiter) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 11200 ug/kg/14D-I
- TOXIC EFFECTS :
- Endocrine - changes in adrenal weight
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 4200 mg/kg
- SEX/DURATION :
- female 9-14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 300 mg/kg
- SEX/DURATION :
- female 9-14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1800 mg/kg
- SEX/DURATION :
- female 9-14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 6 gm/kg
- SEX/DURATION :
- female 7-12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Effects on Newborn - stillbirth Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 12 gm/kg
- SEX/DURATION :
- female 7-12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 300 mg/kg
- SEX/DURATION :
- female 7-12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 3 gm/kg
- SEX/DURATION :
- female 7-12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetal death
MUTATION DATA
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TEST SYSTEM :
- Mold - Aspergillus nidulans
- DOSE/DURATION :
- 1 gm/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 26,159,1974
磺胺林安全信息
[ 危害码 (欧洲) ]:
Xi
[ 风险声明 (欧洲) ]:
R36/37/38:Irritating to eyes, respiratory system and skin .
[ 安全声明 (欧洲) ]:
S26-S36
[ WGK德国 ]:
3
[ 海关编码 ]:
2935009090
磺胺林合成路线
磺胺林上下游产品
磺胺林上游产品
磺胺林下游产品
磺胺林海关
[ 海关编码 ]: 2935009090
[ 中文概述 ]:
2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:35.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%
相关化工产品/化学物质：
推荐生产厂家/供应商：
公司名：上海化源世纪贸易有限公司
区域：上海市普陀区
价格：
联系人：徐经理
产品详情：磺胺林
公司名：上海吉至生化科技有限公司
区域：上海市奉贤区
价格：
￥1128.0/5g
联系人：刘佳
产品详情：磺胺林
公司名：上海源溪生物科技有限公司
区域：上海市浦东新区
价格：
￥需询单/1g
联系人：赖经理
产品详情：AS-18908
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥123.9/1g
￥582.9/25g
￥168.9/5g
￥514.9/1ml
联系人：阿拉丁
产品详情：磺胺林
公司名：上海创赛科技有限公司
区域：上海市嘉定区
价格：
￥1979.0/25g
￥275.0/1g
￥831.0/5g
联系人：夏言
产品详情：[Perfemiker]磺胺林,≥98%
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相关化合物
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