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10-羟基癸酸

10-羟基癸酸用途

10-Hydroxydecanoic acid (NSC 15139) 为 10-hydroxy-trans-2-decenoic acid 的饱和脂肪酸,存在于蜂王浆中,具有抗炎作用。

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10-羟基癸酸名称

[ CAS 号 ]:
1679-53-4

[ 中文名 ]:
10-羟基癸酸

[ 英文名 ]:
10-Hydroxydecanoic acid

[中文别名 ]:

[英文别名 ]:

10-hydroxy-decanoic acid
Decanoic acid, 10-hydroxy-
10-Hydroxy-decansaeure
10-hydroxycapric acid
10-Hydroxycapricacid
10-HYDROXY-DECYLIC ACID
EINECS 216-848-1
MFCD00010510
10-Hydroxydecanoic acid
Decanoic acid,10-hydroxy

10-羟基癸酸生物活性

[ 描述 ]:

10-Hydroxydecanoic acid (NSC 15139) 为 10-hydroxy-trans-2-decenoic acid 的饱和脂肪酸,存在于蜂王浆中,具有抗炎作用。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 炎症/免疫

[参考文献]

[1]. Takahashi K, et al. Inhibitory effect of 10-hydroxydecanoic acid on lipopolysaccharide-induced nitric oxide production via translational downregulation of interferon regulatory factor-1 in RAW264 murine macrophages. Biomed Res. 2013 Aug;34(4):205-14.

10-羟基癸酸物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
330.8±15.0 °C at 760 mmHg

[ 熔点 ]:
75-77 °C(lit.)

[ 分子式 ]:
C₁₀H₂₀O₃

[ 分子量 ]:
188.26

[ 闪点 ]:
168.1±16.9 °C

[ 精确质量 ]:
188.141251

[ PSA ]:
57.53000

[ LogP ]:
1.96

[ 外观性状 ]:
结晶

[ 蒸汽压 ]:
0.0±1.6 mmHg at 25°C

[ 折射率 ]:
1.466

[ 储存条件 ]:
室温

10-羟基癸酸MSDS

10-羟基癸酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2942000000

10-羟基癸酸合成路线

10-羟基癸酸上下游产品

10-羟基癸酸上游产品

10-羟基癸酸下游产品

10-羟基癸酸制备

由蓖麻油裂解而得

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10-羟基癸酸海关

[ 海关编码 ]: 2918199090

[ 中文概述 ]:
HS: 2918199090. 其他含醇基但不含其他含氧基羧酸（包括其酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

10-羟基癸酸文献

Polymerization of 10-hydroxydecanoic acid in benzene with polyethylene glycol-modified lipase. Ajima A, et al.

Biotechnol. Lett. 7(5) , 303-306, (1985)

Lipase-catalyzed synthesis of an epoxy-functionalized polyester from the suberin monomer cis-9,10-epoxy-18-hydroxyoctadecanoic acid.

Biomacromolecules 8(2) , 757-60, (2007)

Estrogenic activities of Fatty acids and a sterol isolated from royal jelly.

Evid. Based. Complement. Alternat. Med. 5(3) , 295-302, (2008)

We have previously reported that royal jelly (RJ) from honeybees (Apis mellifera) has weak estrogenic activity mediated by interaction with estrogen receptors that leads to changes in gene expression ...

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