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2-[(2-苯乙基)氨基]苯甲酸

2-[(2-苯乙基)氨基]苯甲酸用途

恩非那酸是一种非甾体抗炎药。安芬那酸抑制伤口愈合[1][2]。

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2-[(2-苯乙基)氨基]苯甲酸名称

[ CAS 号 ]:
23049-93-6

[ 中文名 ]:
因法来酸

[ 英文名 ]:
Enfenamic acid

[中文别名 ]:

2-[(2-苯基乙基)氨基]苯甲酸

[英文别名 ]:

Enfenamic acid
N-phenylethylanthranilic acid
N-Phenethylanthranilic acid
RH-8
Tromaril

2-[(2-苯乙基)氨基]苯甲酸生物活性

[ 描述 ]:

恩非那酸是一种非甾体抗炎药。安芬那酸抑制伤口愈合[1][2]。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 炎症/免疫

[参考文献]

[1]. Rao CM, et al. Effects of enfenamic acid and its zinc salt on wound-healing. Indian J Physiol Pharmacol. 1988;32(1):61-66.

[2]. Diwan PV, et al. Effects of nonsteroidal antiinflammatory agents (NSAIAs) on wound healing. Indian J Exp Biol. 1986;24(10):640-643.

2-[(2-苯乙基)氨基]苯甲酸物理化学性质

[ 密度 ]:
1.214g/cm3

[ 沸点 ]:
452.3ºC at 760 mmHg

[ 分子式 ]:
C₁₅H₁₅NO₂

[ 分子量 ]:
241.28500

[ 闪点 ]:
227.4ºC

[ 精确质量 ]:
241.11000

[ PSA ]:
49.33000

[ LogP ]:
3.11240

[ 蒸汽压 ]:
5.7E-09mmHg at 25°C

[ 折射率 ]:
1.643

[ 储存条件 ]:
2-8°C，干燥，密封

2-[(2-苯乙基)氨基]苯甲酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DH6286100

CHEMICAL NAME :: Benzoic acid, 2-(phenethylamino)-

CAS REGISTRY NUMBER :: 23049-93-6

LAST UPDATED :: 199612

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C15-H15-N-O2

MOLECULAR WEIGHT :: 241.31

WISWESSER LINE NOTATION :: QVR BM2R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 575 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: Micronucleus test

TYPE OF TEST :: Cytogenetic analysis

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 3 gm/kg/5D (Continuous)

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 170,41,1986

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2-[(2-苯乙基)氨基]苯甲酸安全信息

[ 海关编码 ]:
2922499990

2-[(2-苯乙基)氨基]苯甲酸合成路线

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2-[(2-苯乙基)氨基]苯甲酸上下游产品

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2-[(2-苯乙基)氨基]苯甲酸海关

[ 海关编码 ]: 2922499990

[ 中文概述 ]:
2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: P.进境动植物、动植物产品检疫 Q.出境动植物、动植物产品检疫 R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%