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噻唑

噻唑用途

用作有机合成试剂，用于合成药物、染料、橡胶促进剂、胶片成色剂等

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噻唑名称

[ CAS 号 ]:
288-47-1

[ 中文名 ]:
噻唑

[ 英文名 ]:
Thiazole

[中文别名 ]:

[英文别名 ]:

FEMA 3615
THIAN-4-ONEOXIME
thiazol
MFCD00005315
Thiazole
FEMA NUMBER 3615
EINECS 206-021-3
1,3-Thiazole

噻唑物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
116.5±9.0 °C at 760 mmHg

[ 熔点 ]:
-33°C

[ 分子式 ]:
C₃H₃NS

[ 分子量 ]:
85.128

[ 闪点 ]:
22.2±0.0 °C

[ 精确质量 ]:
84.998619

[ PSA ]:
41.13000

[ LogP ]:
0.44

[ 外观性状 ]:
无色透明液体

[ 蒸汽压 ]:
21.6±0.2 mmHg at 25°C

[ 折射率 ]:
1.543

[ 储存条件 ]:
Flammables area

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents.

[ 水溶解性 ]:
slightly soluble

噻唑MSDS

噻唑毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XJ1290000

CHEMICAL NAME :: Thiazole

CAS REGISTRY NUMBER :: 288-47-1

BEILSTEIN REFERENCE NO. :: 0103852

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C3-H3-N-S

MOLECULAR WEIGHT :: 85.13

WISWESSER LINE NOTATION :: T5N CSJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 983 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 4 umol/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 321,213,1994 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83284 No. of Facilities: 14 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 212 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83284 No. of Facilities: 14 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 1849 (estimated) No. of Female Employees: 272 (estimated)

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噻唑安全信息

[ 符号 ]:

GHS02, GHS05, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H226-H302-H315-H318-H335

[ 警示性声明 ]:
P261-P280-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R10;R22

[ 安全声明 (欧洲) ]:
S16-S26-S39

[ 危险品运输编码 ]:
UN 1993 3/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
XJ1290000

[ 包装等级 ]:
II

[ 危险类别 ]:
3

[ 海关编码 ]:
2934100090

噻唑合成路线

噻唑上下游产品

噻唑上游产品

噻唑下游产品

噻唑制备

用氯乙醛与硫代甲酰胺反应制取。

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噻唑海关

[ 海关编码 ]: 2934100090

[ 中文概述 ]:
2934100090. 结构上含有一个非稠合噻唑环的化合物(不论是否氢化). 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

噻唑文献

CYP3A5 regulates prostate cancer cell growth by facilitating nuclear translocation of AR.

Prostate 75(5) , 527-38, (2015)

The central role of androgen receptor (AR) signaling is established in prostate cancer growth and progression. We propose CYP3A5 is part of a feedback loop that modulates the sensitivity of AR to andr...

Cytotoxic and apoptotic effects of synthetic benzochromene derivatives on human cancer cell lines.

Naunyn Schmiedebergs Arch. Pharmacol. 387(12) , 1199-208, (2014)

With the aim of discovering potential cytotoxic agents, a series of benzochromene derivatives were screened for their cytotoxic activity against seven human cancer cell lines by standard 3-(4, 5-dimet...

Bioactive thermoresponsive polyblend nanofiber formulations for wound healing.

Mater. Sci. Eng. C. Mater. Biol. Appl. 48 , 126-37, (2015)

The rationale of this work is to develop new bioactive thermoresponsive polyblend nanofiber formulations for wound healing (topical). Various polymer compositions of thermoresponsive, poly(N-isopropyl...

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噻唑

噻唑用途

噻唑名称

噻唑物理化学性质

噻唑MSDS

详细MSDS(安全技术说明书)

噻唑毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

噻唑安全信息

噻唑合成路线

详细合成路线

噻唑上下游产品

噻唑上游产品

噻唑下游产品

噻唑制备

噻唑海关

噻唑文献

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