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尼泊金丙酯钠

尼泊金丙酯钠用途

Propylparaben sodium 是一种抗菌剂、防腐剂、调味剂。

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尼泊金丙酯钠名称

[ CAS 号 ]:
35285-69-9

[ 中文名 ]:
对羟基苯甲酸丙酯钠

[ 英文名 ]:
Propylparaben sodium

[中文别名 ]:

[英文别名 ]:

Propylparaben sodium
SODIUM PROPYLPARABEN
EINECS 252-488-1
4-Hydroxybenzoic acid, propyl ester, sodium salt
Natrium propyl 4-hydroxybenzoat
Propylparaben sodium salt
Sodium propyl 4-hydroxybenzoate
MFCD00016477
sodium 4-propoxycarbonylphenoxide
propyl p-hydroxybenzoate sodium salt

尼泊金丙酯钠生物活性

[ 描述 ]:

Propylparaben sodium 是一种抗菌剂、防腐剂、调味剂。

[ 相关类别 ]:

研究领域 >> 感染

信号通路 >> 抗感染 >> 细菌

[参考文献]

[1]. S Oishi, et al. Effects of propyl paraben on the male reproductive system. Food Chem Toxicol. 2002 Dec;40(12):1807-13.

尼泊金丙酯钠物理化学性质

[ 沸点 ]:
294.3ºC at 760 mmHg

[ 熔点 ]:
96-97ºC

[ 分子式 ]:
C₁₀H₁₁NaO₃

[ 分子量 ]:
202.182

[ 闪点 ]:
124.6ºC

[ 精确质量 ]:
202.060593

[ PSA ]:
49.36000

[ LogP ]:
2.39720

[ 外观性状 ]:
白色吸湿的粉末

[ 储存条件 ]:
室温

尼泊金丙酯钠MSDS

尼泊金丙酯钠毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DH2850000

CHEMICAL NAME :: Benzoic acid, p-hydroxy-, propyl ester, sodium deriv.

CAS REGISTRY NUMBER :: 35285-69-9

LAST UPDATED :: 199107

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C10-H11-O3.Na

MOLECULAR WEIGHT :: 202.20

WISWESSER LINE NOTATION :: OR DVO3 &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3700 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 45,260,1956

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 490 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay)

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 45,260,1956

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 45,260,1956

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 85 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRSTAT Drug Standards. (Washington, DC) V.19-28, 1951-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 20,89,1952

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尼泊金丙酯钠安全信息

[ 危害码 (欧洲) ]:
C

[ 安全声明 (欧洲) ]:
22-24/25

[ WGK德国 ]:
2

[ RTECS号 ]:
DH2850000

[ 海关编码 ]:
2918290000

尼泊金丙酯钠合成路线

尼泊金丙酯钠上下游产品

尼泊金丙酯钠上游产品

尼泊金丙酯钠下游产品

尼泊金丙酯钠海关

[ 海关编码 ]: 2909500000

[ 中文概述 ]:
2909500000. 醚酚、醚醇酚及其卤化、磺化、硝化或亚硝化衍生物. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2909500000 ether-phenols, ether-alcohol-phenols and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%