< 生产厂家价格 >

甲基胺草磷

甲基胺草磷用途

甲基阿米普罗福斯(BAY-NTN 6867)是一种磷酸酰胺除草剂。甲基阿米普罗福斯是一种特效的抗微管药物。甲基阿米普罗福斯直接毒害植物细胞中的微管动力学[1]。

点击显示

甲基胺草磷名称

[ CAS 号 ]:
36001-88-4

[ 中文名 ]:
甲基胺草磷

[ 英文名 ]:
Amiprofos methyl

[中文别名 ]:

甲基消草磷

[英文别名 ]:

Amiprofos methyl
amiprophos-methyl

甲基胺草磷生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 细胞周期/DNA损伤 >> 微管/微管蛋白

信号通路 >> 细胞骨架 >> 微管/微管蛋白

[体外研究]

甲基阿米普罗福斯(APM)竞争性抑制[14C]米扎林与微管蛋白的结合,Ki=5μM。抑制烟草细胞生长的甲基阿米普罗福斯浓度在解聚细胞微管的甲基阿米普罗福斯浓度的阈值范围内,表明生长抑制是由微管解聚引起的[2]。

[参考文献]

[1]. Morejohn LC, et al. Inhibition of Plant Microtubule Polymerization in vitro by the Phosphoric Amide Herbicide Amiprophos-Methyl. Science. 1984;224(4651):874-876.

[2]. Murthy JV, et al. Competitive Inhibition of High-Affinity Oryzalin Binding to Plant Tubulin by the Phosphoric Amide Herbicide Amiprophos-Methyl. Plant Physiol. 1994;105(1):309-320.

甲基胺草磷物理化学性质

[ 密度 ]:
1.275g/cm3

[ 沸点 ]:
389.9ºC at 760mmHg

[ 熔点 ]:
-65ºC

[ 分子式 ]:
C₁₁H₁₇N₂O₄PS

[ 分子量 ]:
304.30

[ 闪点 ]:
189.6ºC

[ 精确质量 ]:
304.06500

[ PSA ]:
118.21000

[ LogP ]:
4.71560

[ 折射率 ]:
1.553

[ 储存条件 ]:
库房通风低温干燥

甲基胺草磷MSDS

详细MSDS(安全技术说明书)

甲基胺草磷毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TB5100000

CHEMICAL NAME :: Phosphoramidothioic acid, N-isopropyl-, O-methyl O-(2-nitro-p-tolyl) ester

CAS REGISTRY NUMBER :: 36001-88-4

LAST UPDATED :: 199710

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C11-H17-N2-O4-P-S

MOLECULAR WEIGHT :: 304.33

WISWESSER LINE NOTATION :: WNR C1 FOPS&O1&MY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 309 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85ARAE "Agricultural Chemicals," Thomson, W.T., 4 vols., Fresno, CA, Thomson Publications, 1976/77 revision Volume(issue)/page/year: 2,212,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: SHBOAO Shokubutsu Boeki. (Nippon Shokubutsu Boeki Kyokai, 43-11, Komagome 1-chome, Toshima-Ku, Tokyo, Japan) V.1- 1947- Volume(issue)/page/year: 32,488,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 540 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: SHBOAO Shokubutsu Boeki. (Nippon Shokubutsu Boeki Kyokai, 43-11, Komagome 1-chome, Toshima-Ku, Tokyo, Japan) V.1- 1947- Volume(issue)/page/year: 32,488,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: SHBOAO Shokubutsu Boeki. (Nippon Shokubutsu Boeki Kyokai, 43-11, Komagome 1-chome, Toshima-Ku, Tokyo, Japan) V.1- 1947- Volume(issue)/page/year: 32,488,1978

点击显示

甲基胺草磷安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
R22

[ 安全声明 (欧洲) ]:
36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
TB5100000

[ 海关编码 ]:
2929909011

甲基胺草磷制备

制25.5g邻硝基对甲酚和27.5g O-甲基硫代磷酰二氯完全溶解，加入30mL丙酮，在20～30℃下滴加7.2g氢氧化钠配成的25%碱液。加毕后继续搅拌1h。反应液由橘红变橘黄，加120mL苯，滴加28.3mL异丙胺，滴毕后继续搅拌1h，分离有机层，用水洗至中性，蒸去溶剂得浅黄色产物38.0g，收率70%,m.p.63～64℃。

点击显示

甲基胺草磷海关

[ 海关编码 ]: 2929909011

[ 中文概述 ]:
2929909011 胺丙畏、胺草磷、抑草磷，丁苯草酮等〔包括甲基胺草磷〕退税率:9.0% 监管条件:S(进出口农药登记证明)

[ Summary ]:
2929909011 o-methyl o-(4-methyl-2-nitrophenyl) isopropylphosphoramidothioate

甲基胺草磷文献

Blockage of mitosis in maize root tips using colchicine-alternatives.

Protoplasma 241(1-4) , 99-104, (2010)

Mitosis in plants can be blocked by colchicine which has the capacity to bind microtubule subunits. In maize (Zea mays L.) breeding, it is frequently being used for doubling chromosome numbers of hapl...

In vivo dynamics and differential microtubule-binding activities of MAP65 proteins.

Plant Physiol. 136(4) , 3956-67, (2004)

Plant cells produce different microtubule arrays that are essential for cell division and morphogenesis without equivalent in other eukaryotes. Microtubule-associated proteins influence the behavior o...

Microtubule distribution in gravitropic protonemata of the moss Ceratodon.

Protoplasma 159 , 60-9, (1990)

Tip cells of dark-grown protonemata of the moss Ceratodon purpureus are negatively gravitropic (grow upward). They possess a unique longitudinal zonation: (1) a tip group of amylochloroplasts in the a...

更多文献

甲基胺草磷

甲基胺草磷用途

甲基胺草磷名称

甲基胺草磷生物活性

甲基胺草磷物理化学性质

甲基胺草磷MSDS

详细MSDS(安全技术说明书)

甲基胺草磷毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

甲基胺草磷安全信息

甲基胺草磷制备

甲基胺草磷海关

甲基胺草磷文献

相关化工产品/化学物质：

推荐生产厂家/供应商：

相关化合物