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磺胺托嘧啶

磺胺托嘧啶用途

磺胺甲脒是一种抗菌剂[1]。

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磺胺托嘧啶名称

[ CAS 号 ]:
3772-76-7

[ 中文名 ]:
磺胺托嘧啶

[ 英文名 ]:
Sulfamethomidine

[英文别名 ]:

Methofazine
Duroprocin
Sulfametomidina [INN-Spanish]
Sulfamethomidine
Sulfametomidine
Methofadin
SA 412
EINECS 223-219-5
Sulfametomidinum [INN-Latin]
Solfametomidina [DCIT]

磺胺托嘧啶生物活性

[ 描述 ]:

磺胺甲脒是一种抗菌剂[1]。

[ 相关类别 ]:

研究领域 >> 感染

信号通路 >> 抗感染 >> 细菌

[参考文献]

[1]. TRUANT JP, et al. ENHANCEMENT OF INHIBITORY EFFECT AGAINST GRAM-NEGATIVE ORGANISMS WITH COLISTIN SULFATE AND CERTAIN SULFONAMIDES. Antimicrob Agents Chemother (Bethesda). 1963;161:420-426.

磺胺托嘧啶物理化学性质

[ 密度 ]:
1.418g/cm3

[ 沸点 ]:
501.6ºC at 760mmHg

[ 分子式 ]:
C₁₂H₁₄N₄O₃S

[ 分子量 ]:
294.33000

[ 闪点 ]:
257.2ºC

[ 精确质量 ]:
294.07900

[ PSA ]:
115.58000

[ LogP ]:
2.91160

[ 折射率 ]:
1.633

磺胺托嘧啶毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WP0110000

CHEMICAL NAME :: Sulfanilamide, N(sup 1)-(6-methoxy-2-methyl-4-pyrimidinyl)-

CAS REGISTRY NUMBER :: 3772-76-7

BEILSTEIN REFERENCE NO. :: 0284949

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C12-H14-N4-O3-S

MOLECULAR WEIGHT :: 294.36

WISWESSER LINE NOTATION :: T6N CNJ B1 DO1 FMSWR DZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 3 gm/kg

SEX/DURATION :: female 9-14 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)

REFERENCE :: SEIJBO Senten Ijo. Congenital Anomalies. (Nippon Senten Ijo Gakkai, c/o Kinki Daigaku Igakubu Kaibagaku Kyoshitsu, 380 Nishiyama, Sayama-cho, Mirami-Kawachi-gun, Osaka-fu, Japan) V.1-26, 1960-86. For publisher information, see CGANE7. Volume(issue)/page/year: 13,17,1973

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 6 gm/kg

SEX/DURATION :: female 9-14 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

REFERENCE :: SEIJBO Senten Ijo. Congenital Anomalies. (Nippon Senten Ijo Gakkai, c/o Kinki Daigaku Igakubu Kaibagaku Kyoshitsu, 380 Nishiyama, Sayama-cho, Mirami-Kawachi-gun, Osaka-fu, Japan) V.1-26, 1960-86. For publisher information, see CGANE7. Volume(issue)/page/year: 13,7,1973

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 3 gm/kg

SEX/DURATION :: female 7-12 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)

REFERENCE :: SEIJBO Senten Ijo. Congenital Anomalies. (Nippon Senten Ijo Gakkai, c/o Kinki Daigaku Igakubu Kaibagaku Kyoshitsu, 380 Nishiyama, Sayama-cho, Mirami-Kawachi-gun, Osaka-fu, Japan) V.1-26, 1960-86. For publisher information, see CGANE7. Volume(issue)/page/year: 13,17,1973

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磺胺托嘧啶安全信息

[ 海关编码 ]:
2935009090

磺胺托嘧啶合成路线

详细合成路线

磺胺托嘧啶上下游产品

磺胺托嘧啶上游产品

磺胺托嘧啶下游产品

磺胺托嘧啶海关

[ 海关编码 ]: 2935009090

[ 中文概述 ]:
2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:35.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%