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COLCHICEINE, N-DEACETYL-N-METHYL-

COLCHICEINE, N-DEACETYL-N-METHYL-名称

[ CAS 号 ]:
518-11-6

[ 英文名 ]:
COLCHICEINE, N-DEACETYL-N-METHYL-

[英文别名 ]:

Demecolcein
demecolceine
N-Desacetyl-N-methylcolchiceine

COLCHICEINE, N-DEACETYL-N-METHYL-物理化学性质

[ 密度 ]:
1.27g/cm3

[ 沸点 ]:
626.4ºC at 760 mmHg

[ 分子式 ]:
C₂₀H₂₃NO₅

[ 分子量 ]:
357.40000

[ 闪点 ]:
332.6ºC

[ 精确质量 ]:
357.15800

[ PSA ]:
77.02000

[ LogP ]:
3.04280

[ 折射率 ]:
1.608

COLCHICEINE, N-DEACETYL-N-METHYL-毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GH0600000

CHEMICAL NAME :: Colchiceine, N-deacetyl-N-methyl-

CAS REGISTRY NUMBER :: 518-11-6

LAST UPDATED :: 198712

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C20-H23-N-O5

MOLECULAR WEIGHT :: 357.44

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Gastrointestinal - hypermotility, diarrhea

REFERENCE :: PHTXA6 Pharmacology and Toxicology. English translation of FATOAO. (New York, NY) V.20-22, 1957-59. Discontinued. Volume(issue)/page/year: 20,284,1957

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Gastrointestinal - hypermotility, diarrhea

REFERENCE :: PHTXA6 Pharmacology and Toxicology. English translation of FATOAO. (New York, NY) V.20-22, 1957-59. Discontinued. Volume(issue)/page/year: 20,284,1957

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推荐生产厂家/供应商：

公司名：上海化源世纪贸易有限公司

区域：上海市普陀区

价格：

联系人：徐经理

产品详情：Demecolceine

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