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脂磷壁酸

脂磷壁酸用途

脂磷壁酸是金黄色葡萄球菌的细胞壁成分,通过C3诱导和CD55抑制激活补体系统[1]。

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脂磷壁酸名称

[ CAS 号 ]:
56411-57-5

[ 中文名 ]:
脂磷壁酸

[ 英文名 ]:
Lipoteichoic Acid

[英文别名 ]:

MFCD00131526

脂磷壁酸生物活性

[ 描述 ]:

脂磷壁酸是金黄色葡萄球菌的细胞壁成分,通过C3诱导和CD55抑制激活补体系统[1]。

[ 相关类别 ]:

信号通路 >> 免疫及炎症 >> 补充系统

研究领域 >> 炎症/免疫

[参考文献]

[1]. Bong Jun Jung, et al. Lipoteichoic Acid from Staphylococcus aureus Activates the Complement System via C3 Induction and CD55 Inhibition. Microorganisms. 2021 May 24;9(6):1135.

脂磷壁酸物理化学性质

[ 储存条件 ]:
2-8°C

脂磷壁酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

脂磷壁酸文献

Structural basis of the binding of fatty acids to peptidoglycan recognition protein, PGRP-S through second binding site.

Arch. Biochem. Biophys. 529(1) , 1-10, (2013)

Short peptidoglycan recognition protein (PGRP-S) is a member of the mammalian innate immune system. PGRP-S from Camelus dromedarius (CPGRP-S) has been shown to bind to lipopolysaccharide (LPS), lipote...

Lipoteichoic acid from Staphylococcus aureus induces lung endothelial cell barrier dysfunction: role of reactive oxygen and nitrogen species.

PLoS ONE 7(11) , e49209, (2012)

Tunneled central venous catheters (TCVCs) are used for dialysis access in 82% of new hemodialysis patients and are rapidly colonized with Gram-positive organism (e.g. Staphylococcus aureus) biofilm, a...

Lipoteichoic acid from Lactobacillus plantarum inhibits Pam2CSK4-induced IL-8 production in human intestinal epithelial cells.

Mol. Immunol. 64(1) , 183-9, (2015)

Lactobacilli are probiotic bacteria that are considered to be beneficial in the gastrointestinal tract of humans. Although lactobacilli are well known to alleviate intestinal inflammation, the molecul...

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