4-甲氧基-3-羟基苯乙酮

4-甲氧基-3-羟基苯乙酮用途

3-Hydroxy-4-methoxyacetophenone(Acetoisovanillone; Isoacetovanillone) 是从 P. spinosa 中分离得到的一种活性化合物。Isoacetovanillone 具有抗炎活性,可防止醋酸引起的结肠损伤。

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4-甲氧基-3-羟基苯乙酮名称

[ CAS 号 ]:
6100-74-9

[ 中文名 ]:
4-甲氧基-3-羟基苯乙酮

[ 英文名 ]:
Isoacetovanillone

[中文别名 ]:

[英文别名 ]:

isoacetovanillon
1-(3-Hydroxy-4-methoxyphenyl)ethanone
4-Methoxy-3-hydroxyacetophenone
2-hydroxy-4-acetoanisole
3-Hydroxy-4-methoxyacetophenone
Ethanone, 1-(3-hydroxy-4-methoxyphenyl)-
2-methoxy-5-acetylphenol

4-甲氧基-3-羟基苯乙酮生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 炎症/免疫

[参考文献]

[1]. Minaiyan M, et al. Anti-inflammatory effect of Pycnocycla spinosa extract and its component isoacetovanillone on acetic acid induced colitis in rats. Res Pharm Sci. 2015 Jul-Aug;10(4):345-55.

4-甲氧基-3-羟基苯乙酮物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
329.9±27.0 °C at 760 mmHg

[ 熔点 ]:
88-92ºC

[ 分子式 ]:
C₉H₁₀O₃

[ 分子量 ]:
166.174

[ 闪点 ]:
135.7±17.2 °C

[ 精确质量 ]:
166.062988

[ PSA ]:
46.53000

[ LogP ]:
1.25

[ 外观性状 ]:
固体

[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C

[ 折射率 ]:
1.538

[ 储存条件 ]:
室温，干燥

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents.

4-甲氧基-3-羟基苯乙酮安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
22

[ 安全声明 (欧洲) ]:
22

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2914509090

4-甲氧基-3-羟基苯乙酮合成路线

详细合成路线

4-甲氧基-3-羟基苯乙酮上下游产品

4-甲氧基-3-羟基苯乙酮上游产品

4-甲氧基-3-羟基苯乙酮下游产品

4-甲氧基-3-羟基苯乙酮海关

[ 海关编码 ]: 2914509090

[ 中文概述 ]:
2914509090 含其他含氧基的酮. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:5.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 丙酮报明包装

[ Summary ]:
HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

4-甲氧基-3-羟基苯乙酮文献

[Analgesic effect and gastro-intestinal motility inhibitory action of 3-hydroxy-4-methoxy-acetophenone from Cynanchum paniculatum (Bunge) Kitagawa].

Zhongguo Zhong Yao Za Zhi 18(6) , 362-3, 383, (1993)

3-Hydroxy-4-methoxy-acetophenone (HMA) isolated from Cynanchum paniculatum was found to have analgesic effect and inhibitory action on the gastro-intestinal motility. The effect and action were equiva...

Precision studies in supramolecular chemistry: a 1H NMR study of hydroxymethoxyacetophenone/β-cyclodextrin complexes.

Magn. Reson. Chem. 49(7) , 405-12, (2011)

The association constants for the interactions of 2-hydroxy-4-methoxyacetophenone, 2-hydroxy-5-methoxyacetophenone, 2-hydroxy-6-methoxyacetophenone, 3-hydroxy-4-methoxyacetophenone and 4-hydroxy-3-met...

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