2-硝基丙三醇

2-硝基丙三醇名称

[ CAS 号 ]:
620-12-2

[ 中文名 ]:
2-硝基丙三醇

[ 英文名 ]:
2-MONONITROGLYCERIN

[英文别名 ]:

2-Glyceryl mononitrate
2-nitrooxy-propane-1,3-diol
Glycerin 2-nitrate
2-mononitroglycerin
glycerol mononitrate
Glycerol-2-nitrate
Glyceryl 2-nitrate
1,2,3-Propanetriol,2-nitrate
Glycerol 2-mononitrate
Glycerol-2-nitrat

2-硝基丙三醇物理化学性质

[ 密度 ]:
1.48g/cm3

[ 沸点 ]:
157.5ºC at 760 mmHg

[ 分子式 ]:
C₃H₇NO₅

[ 分子量 ]:
137.09100

[ 闪点 ]:
49.1ºC

[ 精确质量 ]:
137.03200

[ PSA ]:
95.51000

[ 折射率 ]:
1.489

2-硝基丙三醇毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MB0290000

CHEMICAL NAME :: Glycerol, 2-nitrate

CAS REGISTRY NUMBER :: 620-12-2

BEILSTEIN REFERENCE NO. :: 1765006

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C3-H7-N-O5

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 36,814,1986

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 36,814,1986

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >8 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 36,814,1986

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 36,814,1986

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2-硝基丙三醇安全信息

[ 符号 ]:

GHS02, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H302 + H332-H319

[ 警示性声明 ]:
P210-P305 + P351 + P338

[ 危险品运输编码 ]:
UN 1648 3 / PGII

[ 海关编码 ]:
2920909090

2-硝基丙三醇合成路线

详细合成路线

2-硝基丙三醇上下游产品

2-硝基丙三醇上游产品

2-硝基丙三醇下游产品

2-硝基丙三醇海关

[ 海关编码 ]: 2920909090

[ 中文概述 ]:
2920909090 其他无机酸酯（不包括卤化氢的酯）（包括其盐及它们的卤化，磺化，硝化和亚硝化衍生物）。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2920909090 esters of other inorganic acids of non-metals (excluding esters of hydrogen halides) and their salts; their halogenated, sulphonated, nitrated or nitrosated derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

2-硝基丙三醇文献

[Comparative hemodynamics action of glycero-2-nitrate and glycerol trinitrate in various species and the pharmacokinetics of glycerol-2-nitrate in the dog].

Arzneimittelforschung 36(12) , 1752-6, (1986)

Comparative Hemodynamic Activity of Glyceryl 2-Nitrate and Glyceryl Trinitrate in Various Species and Pharmacokinetics of Glyceryl 2-Nitrate in Dog A single dose of glyceryl 2-nitrate (G-2-N) had prac...

[The pharmacology and pharmacokinetics of glycerol-2-nitrate].

Arzneimittelforschung 37(6) , 692-8, (1987)

Glyceryl 2-nitrate (G-2-N), which is the major metabolite of glyceryl trinitrate (GTN, Nitro Mack, glyceryl 1-nitrate (G-1-N) and isosorbide-5-nitrate (IS-5-N, Mono Mack) were examined in a comparativ...

Formation of glyceryl 2-mononitrate by regioselective bioconversion of glyceryl trinitrate: efficiency of the filamentous fungus Phanerochaete chrysosporium.

Biotechnol. Appl. Biochem. 12(3) , 325-30, (1990)

Various microorganisms have been evaluated for their ability to hydrolyze glyceryl trinitrate (GTN) to glyceryl dinitrates and mononitrates. Provided that the GTN extracellular concentration was under...

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