1,4-二氧六环
1,4-二氧六环用途
用作醋酸纤维素、树脂、植物油、矿物油、溶性染料等的溶剂,用于制喷漆、清漆、增塑剂、润滑剂等
【用途二】
用作色谱分析试剂及乙酸纤维及其衍生物的溶剂
【用途三】
用作醋酸纤维素、植物油、矿物油、溶性染料等的溶剂,用于制喷漆、清漆、增塑剂、润滑剂等
【用途四】
该品在医药、化妆品、香料等特殊精细化学品制造,以及科学研究中作为溶剂、反应介质、萃取剂使用。在日本,该品主要用作1,1,1-三氯乙烷的稳定剂,添加量为2.5-4%;其次,应用较多的是作为聚氨酯合成革、氨基酸合成革等的反应溶剂。该品溶解能力强,与二甲基甲酰胺相近,比四氢呋喃强。二氧六环有以下用途值得重视:(1)与三氧化硫形成络合物,可用作许多化合物合成时的硫酸化剂;(2)用于医药、农药的提取,石油产品的脱蜡等;(3)用作染料分散剂、木材着色剂的分散剂以及油溶性染料的溶剂;(4)用作高纯度金属表面处理剂等。该品对皮肤、肺、粘膜有刺激性。严重中毒时可损害肝、肾。
1,4-二氧六环名称
[ CAS 号 ]:
123-91-1
[ 中文名 ]:
1,4-二氧六环
[ 英文名 ]:
1,4-Dioxane
[中文别名 ]:
[英文别名 ]:
- DIOXANE, 1,4-
- 1,4-Dioxan
- Diethylene oxide
- MFCD00006571
- para-dioxane
- 1,4-Diethylene Dioxide
- EINECS 204-661-8
1,4-二氧六环物理化学性质
[ 密度 ]:
1.033
[ 沸点 ]:
101 °C
[ 熔点 ]:
12 °C
[ 分子式 ]:
C4H8O2
[ 分子量 ]:
88.10510
[ 闪点 ]:
12 ºC
[ 精确质量 ]:
88.05240
[ PSA ]:
18.46000
[ LogP ]:
0.03320
[ 外观性状 ]:
无色透明液体
[ 蒸汽密度 ]:
3 (vs air)
[ 蒸汽压 ]:
11.2mmHg at 25°C
[ 折射率 ]:
n20/D 1.422(lit.)
[ 储存条件 ]:
库房通风低温干燥,与氧化剂、酸类分开存放
[ 稳定性 ]:
Stable. Incompatible with oxidizing agents, oxygen, halogens, reducing agents, moisture. Highly flammable - note wide explosive range. May form explosive peroxides in storage (rate of formation increased by heating, evaporation or exposure to light).
[ 水溶解性 ]:
SOLUBLE
1,4-二氧六环MSDS
1,4-二氧六环毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- JG8225000
- CHEMICAL NAME :
- p-Dioxane
- CAS REGISTRY NUMBER :
- 123-91-1
- BEILSTEIN REFERENCE NO. :
- 0102551
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 88
- MOLECULAR FORMULA :
- C4-H8-O2
- MOLECULAR WEIGHT :
- 88.12
- WISWESSER LINE NOTATION :
- T6O DOTJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Human
- TYPE OF TEST :
- Open irritation test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - guinea pig
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 470 ppm
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Vascular - BP elevation not characterized in autonomic section Gastrointestinal - other changes
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 5500 ppm/1M
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation Sense Organs and Special Senses (Eye) - conjunctive irritation Lungs, Thorax, or Respiration - other changes
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 470 ppm/3D
- TOXIC EFFECTS :
- Brain and Coverings - other degenerative changes Lungs, Thorax, or Respiration - other changes Liver - other changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7120 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 46 gm/m3/2H
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 799 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 37 gm/m3/2H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 790 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 44 gm/m3/7H
- TOXIC EFFECTS :
- Behavioral - excitement Lungs, Thorax, or Respiration - dyspnea
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 1500 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - irritability
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 7600 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1500 mg/kg
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - urine volume increased Kidney, Ureter, Bladder - urine volume decreased Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 3150 mg/kg
- TOXIC EFFECTS :
- Behavioral - general anesthetic Gastrointestinal - other changes Kidney, Ureter, Bladder - other changes
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 20500 mg/m3
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 6000 ppm/4H/2W-I
- TOXIC EFFECTS :
- Behavioral - changes in psychophysiological tests
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 20500 ug/m3/13W-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - proteinuria Nutritional and Gross Metabolic - changes in chlorine Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 185 gm/kg/2Y-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Liver - tumors
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 111 ppm/7H/2Y-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Blood - tumors Blood - lymphoma, including Hodgkin's disease
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 239 gm/kg/90W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 14 gm/kg/60W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 12 gm/kg/8W-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 416 gm/kg/57W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Liver - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 408 gm/kg/2Y-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Liver - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 523 gm/kg/90W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 416 gm/kg/57W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Liver - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 528 gm/kg/63W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - Kidney tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 10 gm/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- DNA damage
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TYPE OF TEST :
- Micronucleus test
- TYPE OF TEST :
- Micronucleus test
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Ovary
- REFERENCE :
- EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 10(Suppl 10),1,1987 *** REVIEWS *** ACGIH TLV-Animal carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 90 mg/m3 (25 ppm) (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 11,247,1976 IARC Cancer Review:Human Inadequate Evidence IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,201,1987 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,201,1987 TOXICOLOGY REVIEW BNYMAM Bulletin of the New York Academy of Medicine. (New York Academy of Medicine, 2 E. 103rd St., New York, NY 10029) Ser 2: V.1- 1925- Volume(issue)/page/year: 54,413,1978 TOXICOLOGY REVIEW ECIET* European Chemical Industry Ecology and Toxicology Centre. Joint Assessment of Commodity Chemicals. (Avenue Louise 250, B-63, B-1050 Brussels, Belgium) Volume(issue)/page/year: (2),-,1983 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 100 ppm (360 mg/m3) (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,94,1971 OSHA PEL (Gen Indu):8H TWA 100 ppm (360 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 100 ppm (360 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 100 ppm (360 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 100 ppm (360 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 25 ppm (90 mg/m3);Skin JAN 1993 OEL-AUSTRIA:TWA 50 ppm (180 mg/m3);Skin JAN 1993 OEL-BELGIUM:TWA 25 ppm (90 mg/m3);Skin JAN 1993 OEL-DENMARK:TWA 10 ppm (36 mg/m3);Skin JAN 1993 OEL-FINLAND:TWA 25 ppm (90 mg/m3);STEL 40 ppm (135 mg/m3);Skin JAN 1993 OEL-FRANCE:TWA 10 ppm (35 mg/m3);STEL 40 ppm (140 mg/m3);Carcinogen JAN 1993 OEL-GERMANY:TWA 50 ppm (180 mg/m3);Skin;Carcinogen JAN 1993 OEL-HUNGARY:STEL 10 mg/m3;Skin;Carcinogen JAN 1993 OEL-JAPAN:TWA 10 ppm (36 mg/m3);Skin;Carcinogen JAN 1993 OEL-THE NETHERLANDS:TWA 50 ppm (180 mg/m3);Skin JAN 1993 OEL-THE PHILIPPINES:TWA 100 ppm (360 mg/m3);Skin JAN 1993 OEL-POLAND:TWA 10 mg/m3 JAN 1993 OEL-RUSSIA:TWA 10 ppm;STEL 10 mg/m3;Skin JAN 1993 OEL-SWEDEN:TWA 25 ppm (90 mg/m3);STEL 50 ppm;Skin;Carcinogen JAN 1993 OEL-SWITZERLAND:TWA 25 ppm (90 mg/m3);STEL 50 ppm;Skin JAN 1993 OEL-TURKEY:TWA 100 ppm (360 mg/m3);Skin JAN 1993 OEL-UNITED KINGDOM:TWA 25 ppm (90 mg/m3);STEL 100 ppm;Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO DIOXANE-air:CA CL 1 ppm/30M REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 25145 No. of Facilities: 12911 (estimated) No. of Industries: 135 No. of Occupations: 101 No. of Employees: 147783 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 25145 No. of Facilities: 20994 (estimated) No. of Industries: 181 No. of Occupations: 137 No. of Employees: 429330 (estimated) No. of Female Employees: 149697 (estimated)
1,4-二氧六环安全信息
[ 符号 ]:
GHS02, GHS07, GHS08
[ 信号词 ]:
Danger
[ 危害声明 ]:
H225-H319-H335-H351
[ 补充危害声明 ]:
May form explosive peroxides., Repeated exposure may cause skin dryness or cracking.
[ 警示性声明 ]:
P210-P261-P281-P305 + P351 + P338
[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ 危害码 (欧洲) ]:
F:Flammable
[ 风险声明 (欧洲) ]:
R11;R19;R36/37;R40;R66
[ 安全声明 (欧洲) ]:
S9-S16-S36/37-S46-S45-S53-S7-S62-S26-S24/25-S23
[ 危险品运输编码 ]:
UN 1993 3/PG 2
[ WGK德国 ]:
3
[ RTECS号 ]:
JG8225000
[ 包装等级 ]:
II
[ 危险类别 ]:
3
[ 海关编码 ]:
2942000000
1,4-二氧六环合成路线
1,4-二氧六环上下游产品
1,4-二氧六环上游产品
1,4-二氧六环下游产品
1,4-二氧六环制备
精制方法:主要杂质有乙醛、2-甲基-1,3-二戊烷、缩醛、过氧化物及水分。杂质含量不多时,可加金属钠回流6~12小时后,直接进行蒸馏。含有多量的缩醛时,需要进行水解除去。在2L二噁烷中加入27mL浓盐酸和200mL水,回流12小时。在回流过程中漫漫通入氮气以除去生成的乙醛;冷却后加入固体氢氧化钾,直到不再溶解为止。分去水层,再加入氢氧化钾干燥24小时。将初步干燥的二烷加金属钠回流6~12小时,然后在金属钠存在下进行蒸馏。过氧化物的除去与乙醚相同。将粉碎的氢氧化钠加入到工业品二氧六环中,除去酸性物质和水分。滤去固体物质后进行蒸馏,即得纯品二氧六环。
1.乙二醇法 在硫酸催化下脱水而得,其反应式如下:
2.环氧乙烷法 直接经二聚而得,其反应式如下:
上述二聚反应在酸性催化剂存在下进行,催化剂可以是硫酸氢钠、硫酸及三氟化硼等。工业级二氧六环需要精制为纯品时,可将粉状氢氧化钠加入二氧六环中,除去酸性物质和水分,滤去固体物质后蒸馏即得成品。
3.二甘醇法 二甘醇在质子酸作用下分子内脱水制取二烷的主反应如下:
1,4-二氧六环海关
[ 海关编码 ]: 2932999070
[ 申报要素 ]: 品名, 成分含量, 用途
[ 监管条件 ]: X.有毒化学品环境管理放行通知单
[ Summary ]:
2932999070 1,4-dioxane
1,4-二氧六环文献
Adv. Funct. Mater. 25(3) , 350-360, (2015)
Injectable microspheres are attractive stem cell carriers for minimally invasive procedures. For tissue regeneration, the microspheres need to present the critical cues to properly direct stem cell di...
The development of a new disposable pipette extraction phase based on polyaniline composites for the determination of levels of antidepressants in plasma samples.J. Chromatogr. A. 1399 , 1-7, (2015)
In the present work, a new stationary phase for disposable pipette extraction (DPX) based on composites of polyaniline and a styrene-divinylbenzene (SD) copolymer was applied to the analysis of fluoxe...
Selective Solid-Phase Extraction of Zinc(II) from Environmental Water Samples Using Ion Imprinted Activated Carbon.J. AOAC Int. 98(1) , 206-12, (2015)
A simple ion imprinted amino-functionalized sorbent was synthesized by coupling activated carbon with iminodiacetic acid, a functional compound for metal chelating, through cyanoric chloride spacer. T...
相关化工产品/化学物质:
推荐生产厂家/供应商:
公司名:上海化源世纪贸易有限公司
区域:上海市普陀区
价格:
联系人:徐经理
产品详情:1,4-二氧六环
公司名:上海吉至生化科技有限公司
区域:上海市奉贤区
价格:
¥68.0/500ml
¥1478.0/4l
¥138.0/100ml
¥218.0/500ml
联系人:刘佳
产品详情:1,4-二氧六环
公司名:上海阿拉丁生化科技股份有限公司
区域:上海市浦东新区
价格:
¥需询单/1mg
¥需询单/1g
¥需询单/1g
¥需询单/1g
联系人:阿拉丁
产品详情:1,4-二氧六环
公司名:济南世纪通达化工有限公司
区域:济南市天桥区
价格:
¥21500.0/1ton
¥42000.0/2ton
联系人:王经理
产品详情:1,4-二氧六环
公司名:山东金悦源新材料有限公司
区域:济南市天桥区
价格:
¥3600.0/200kg
¥18000.0/1ton
联系人:王思兵
产品详情:1,4-二氧六环
查看所有供应商请点击:
相关化合物
【1,4-二氧六环】化源网提供1,4-二氧六环CAS号123-91-1,1,4-二氧六环MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询1,4-二氧六环上化源网,专业又轻松。>>电脑版:1,4-二氧六环
标题:1,4-二氧六环_MSDS_用途_密度_CAS号【123-91-1】_化源网 地址:https://m.chemsrc.com/mip/cas/123-91-1_390554.html