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甲醯胺肟

甲醯胺肟名称

[ CAS 号 ]:
624-82-8

[ 中文名 ]:
氨基甲肟

[ 英文名 ]:
FORMAMIDOXIME

[中文别名 ]:

甲醯胺肟

[英文别名 ]:

EINECS 210-865-8
carboxamidoxime
Aminoformaldehyde oxime
formamideoxime
N-hydroxycarboximidamide
n-hydroxy-methanimidamid
formamidoxim
n-hydroxymethanimidamide
isuretin
MFCD00008125

甲醯胺肟物理化学性质

[ 密度 ]:
1.29g/cm3

[ 沸点 ]:
224ºC at 760 mmHg

[ 熔点 ]:
112-115ºC(lit.)

[ 分子式 ]:
CH₄N₂O

[ 分子量 ]:
60.05530

[ 闪点 ]:
89.3ºC

[ 精确质量 ]:
60.03240

[ PSA ]:
58.61000

[ LogP ]:
0.06290

[ 折射率 ]:
1.471

[ 储存条件 ]:
2-8°C

甲醯胺肟MSDS

甲醯胺肟毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LQ4632000

CHEMICAL NAME :: Formamidoxime

CAS REGISTRY NUMBER :: 624-82-8

LAST UPDATED :: 199304

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C-H4-N2-O

MOLECULAR WEIGHT :: 60.07

WISWESSER LINE NOTATION :: QM1UM

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 350 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 18,645,1968

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甲醯胺肟安全信息

[ 符号 ]:

GHS07, GHS08

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302 + H312 + H332-H351

[ 警示性声明 ]:
P280

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
20/21/22-40

[ 安全声明 (欧洲) ]:
22-36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
LQ4632000

[ 海关编码 ]:
2925290090

甲醯胺肟合成路线

甲醯胺肟上下游产品

甲醯胺肟上游产品

甲醯胺肟下游产品

甲醯胺肟海关

[ 海关编码 ]: 2925290090

[ 中文概述 ]:
2925290090 其他亚胺及其衍生物，以及它们的盐。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

甲醯胺肟文献

Antitumor activity of amidoximes (hydroxyurea analogs) in murine tumor systems.

Cancer Res. 38(5) , 1291-5, (1978)

A series of amidoximes was prepared and evaluated for possible antitumor activity against L1210 leukemia. Three of the most active compounds in the L1210 system, formamidoxime, acetamidoxime, and 2-am...

Nitric oxide synthesis by tracheal smooth muscle cells by a nitric oxide synthase-independent pathway.

Am. J. Physiol. 275(5 Pt 1) , L895-901, (1998)

Nitric oxide (NO) is known to be synthesized from L-arginine in a reaction catalyzed by NO synthase. Liver cytochrome P-450 enzymes also catalyze the oxidative cleavage of C==N bonds of compounds cont...

Effects of phenobarbital, beta-naphthoflavone, dexamethasone, and formamidoxime on the turnover of inducible microsomal proteins in cultured hepatocytes.

J. Biol. Chem. 256(24) , 13079-84, (1981)

Microsomal proteins from cultured chick embryo hepatocytes were separated by polyacrylamide gel electrophoresis and their rate constants of degradation (Kd) were estimated using double isotope techniq...

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