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去氧皮质酮

去氧皮质酮用途

Deoxycorticosterone是由肾上腺产生的类固醇激素,其具有盐皮质激素活性并且充当醛固酮前体。

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去氧皮质酮名称

[ CAS 号 ]:
64-85-7

[ 中文名 ]:
去氧皮质酮

[ 英文名 ]:
Desoxycorticosterone

[中文别名 ]:

[英文别名 ]:

EINECS 200-596-4
Desoxycorticosterone
MFCD00003661

去氧皮质酮生物活性

[ 描述 ]:

Deoxycorticosterone是由肾上腺产生的类固醇激素,其具有盐皮质激素活性并且充当醛固酮前体。

[ 相关类别 ]:

天然产物 >> 其他

研究领域 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. KAGAWA CM, et al. Action of new steroids in blocking effects of aldosterone and desoxycorticosterone on salt. Science. 1957 Nov 15;126(3281):1015-6.

[相关活性小分子]

去氧皮质酮物理化学性质

[ 密度 ]:
1.15 g/cm3

[ 沸点 ]:
488ºC at 760 mmHg

[ 熔点 ]:
138-144 °C

[ 分子式 ]:
C₂₁H₃₀O₃

[ 分子量 ]:
330.46100

[ 闪点 ]:
263.1ºC

[ 精确质量 ]:
330.21900

[ PSA ]:
54.37000

[ LogP ]:
3.69590

[ 外观性状 ]:
白色至奶油色-白色结晶粉末

[ 折射率 ]:
1.559

[ 储存条件 ]:
2-8℃

[ 水溶解性 ]:
slightly soluble

去氧皮质酮MSDS

去氧皮质酮毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HG0350000

CHEMICAL NAME :: 11-Deoxycorticosterone

CAS REGISTRY NUMBER :: 64-85-7

LAST UPDATED :: 199703

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C21-H30-O3

MOLECULAR WEIGHT :: 330.51

WISWESSER LINE NOTATION :: L E5 B666 OV MUTJ A E FV1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intramuscular

DOSE :: 14500 ug/kg

SEX/DURATION :: female 7 day(s) pre-mating female 1-22 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - delayed effects

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Parenteral

DOSE :: 8750 ug/kg

SEX/DURATION :: female 7 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - uterus, cervix, vagina

MUTATION DATA

TYPE OF TEST :: DNA adduct

TEST SYSTEM :: Human Liver

DOSE/DURATION :: 2 mmol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 370,49,1996

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去氧皮质酮安全信息

[ 符号 ]:

GHS02, GHS06, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H301 + H311 + H331-H370

[ 警示性声明 ]:
P210-P260-P280-P301 + P310-P311

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
R40;R48

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
UN 2811 6.1/PG 2

[ WGK德国 ]:
3

[ RTECS号 ]:
HG0350000

[ 海关编码 ]:
2942000000

去氧皮质酮合成路线

去氧皮质酮上下游产品

去氧皮质酮上游产品

去氧皮质酮下游产品

去氧皮质酮制备

用其醋酸酯水解制得该品。

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去氧皮质酮海关

[ 海关编码 ]: 2942000000

去氧皮质酮文献

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The current study has proved the technical feasibility of including electrochemical advanced oxidation processes (EAOPs) in a multistage strategy for the remediation of a sanitary landfill leachate th...

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Water Res. 83 , 31-41, (2015)

The degradation of 100 mL of 0.245 mM of the antibiotic ciprofloxacin in 0.05 M Na2SO4 at pH 3.0 has been studied by electrochemical oxidation with electrogenerated H2O2 (EO-H2O2), electro-Fenton (EF)...

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J. Med. Chem. 58 , 4250-65, (2015)

Selenium-containing chrysin (SeChry) and 3,7,3',4'-tetramethylquercetin (SePQue) derivatives were synthesized by a microwave-based methodology. In addition to their improvement in terms of DPPH scaven...

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去氧皮质酮

去氧皮质酮用途

去氧皮质酮名称

去氧皮质酮生物活性

去氧皮质酮物理化学性质

去氧皮质酮MSDS

详细MSDS(安全技术说明书)

去氧皮质酮毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

去氧皮质酮安全信息

去氧皮质酮合成路线

详细合成路线

去氧皮质酮上下游产品

去氧皮质酮上游产品

去氧皮质酮下游产品

去氧皮质酮制备

去氧皮质酮海关

去氧皮质酮文献

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