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N-乙酰-L-蛋氨酸

N-乙酰-L-蛋氨酸用途

N-Acetyl-L-methionine 是一种人体代谢物,在营养和代谢作用上和 L-methionine相当。L-methionine 是生长发育并不可少的氨基酸。

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N-乙酰-L-蛋氨酸名称

[ CAS 号 ]:
65-82-7

[ 中文名 ]:
N-乙酰-L-蛋氨酸

[ 英文名 ]:
N-acetyl-L-methionine

[中文别名 ]:

[英文别名 ]:

EINECS 200-617-7
MFCD00064441
N-Acetyl-L-methionine
N-acetyl-methionine
Thiomedon
L-Methionine, N-acetyl-
(2S)-2-acetamido-4-methylsulfanylbutanoic acid
Acetylmethionine
Methionine, N-acetyl-, L-
Methionamine

N-乙酰-L-蛋氨酸生物活性

[ 描述 ]:

N-Acetyl-L-methionine 是一种人体代谢物,在营养和代谢作用上和 L-methionine相当。L-methionine 是生长发育并不可少的氨基酸。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 代谢疾病

[参考文献]

[1]. Ball RO, et al. The in vivo sparing of methionine by cysteine in sulfur amino acid requirements in animal models and adult humans. J Nutr. 2006 Jun;136(6 Suppl):1682S-1693S.

N-乙酰-L-蛋氨酸物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
371.3±52.0 °C at 760 mmHg

[ 熔点 ]:
104-107ºC

[ 分子式 ]:
C₇H₁₃NO₃S

[ 分子量 ]:
191.248

[ 闪点 ]:
178.3±30.7 °C

[ 精确质量 ]:
191.061615

[ PSA ]:
91.70000

[ LogP ]:
0.95

[ 外观性状 ]:
白色晶体

[ 蒸汽压 ]:
0.0±1.9 mmHg at 25°C

[ 折射率 ]:
1.532

[ 储存条件 ]:
库房通风低温干燥

N-乙酰-L-蛋氨酸MSDS

详细MSDS(安全技术说明书)

N-乙酰-L-蛋氨酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: PD0480000

CHEMICAL NAME :: Methionine, N-acetyl-

CAS REGISTRY NUMBER :: 65-82-7

BEILSTEIN REFERENCE NO. :: 1725552

LAST UPDATED :: 199709

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C7-H13-N-O3-S

MOLECULAR WEIGHT :: 191.27

WISWESSER LINE NOTATION :: 1VMYVQ2S1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 435 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RPOBAR Research Progress in Organic-Biological and Medicinal Chemistry. (New York, NY) V.1-3, 1964-72. Discontinued. Volume(issue)/page/year: 2,262,1970

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N-乙酰-L-蛋氨酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
PD0480000

[ 海关编码 ]:
29309070

N-乙酰-L-蛋氨酸上下游产品

N-乙酰-L-蛋氨酸上游产品

N-乙酰-L-蛋氨酸下游产品

N-乙酰-L-蛋氨酸海关

[ 海关编码 ]: 29309070

N-乙酰-L-蛋氨酸文献

Importance of product inhibition in the kinetics of the acylase hydrolysis reaction by differential stopped flow microcalorimetry.

Anal. Biochem. 308 , 285-293, (2002)

The hydrolysis of N-acetyl-L-methionine, N-acetylglycine, N-acetyl-L-phenylalanine, and N-acetyl-L-alanine at 298.35K by porcine kidney acylase I (EC 3.5.1.14) was monitored by the heat released upon ...

Model sclerotization studies. 4. Generation of N-acetylmethionyl catechol adducts during tyrosinase-catalyzed oxidation of catechols in the presence of N-acetylmethionine.

Arch. Insect Biochem. Physiol. 38(1) , 44-52, (1998)

Incubation of catechol with mushroom tyrosinase in the presence of N-acetylmethionine resulted in the generation of an adduct. This product was identified to be N-acetylmethionyl catechol, on the basi...

Identification of N-acetylmethionine as the product released during the NH2-terminal processing of a pseudo-class I actin.

J. Biol. Chem. 264(19) , 11491-6, (1989)

Genes for the various isoactins define two classes of actin. Class I actin genes code for Met-Asp(Glu)-actin, and class II actin genes code for Met-X-Asp(Glu)-actin where X is usually cysteine. Amino ...

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