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L-(-)-阿拉伯糖醇

L-(-)-阿拉伯糖醇用途

L-Arabinitol 是甘薯,鹿梅,乌头叶菜豆等食物摄入的生物标记,也被发现和人类阿尔兹海默,症5-磷酸异构酶缺乏症相关。

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L-(-)-阿拉伯糖醇名称

[ CAS 号 ]:
7643-75-6

[ 中文名 ]:
L-(-)-阿拉伯糖醇

[ 英文名 ]:
L-(−)-Arabitol

[中文别名 ]:

[英文别名 ]:

L-ARA-OL
(2S,4S)-pentane-1,2,3,4,5-pentol
L(-)-ARABIT
L-(-)-Arabitol
MFCD00064290
L-Arabite
L-Arabinitol
arabinitol
EINECS 231-582-6
(2S,4S)-1,2,3,4,5-Pentanepentol

L-(-)-阿拉伯糖醇生物活性

[ 描述 ]:

L-Arabinitol 是甘薯,鹿梅,乌头叶菜豆等食物摄入的生物标记,也被发现和人类阿尔兹海默,症5-磷酸异构酶缺乏症相关。

[ 相关类别 ]:

天然产物 >> 其他

研究领域 >> 代谢疾病

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Shetty HU, et al. Cerebrospinal fluid and plasma distribution of myo-inositol and other polyols in Alzheimer disease. Clin Chem. 1996 Feb;42(2):298-302.

[相关活性小分子]

L-(-)-阿拉伯糖醇物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
494.5±40.0 °C at 760 mmHg

[ 熔点 ]:
101-104ºC(lit.)

[ 分子式 ]:
C₅H₁₂O₅

[ 分子量 ]:
152.146

[ 闪点 ]:
261.9±21.9 °C

[ 精确质量 ]:
152.068466

[ PSA ]:
101.15000

[ LogP ]:
-3.77

[ 外观性状 ]:
白色非晶形的粉末

[ 蒸汽压 ]:
0.0±2.9 mmHg at 25°C

[ 折射率 ]:
1.571

[ 储存条件 ]:
Refrigerator (+4°C)

[ 水溶解性 ]:
H2O: 0.1 g/mL, clear, colorless

L-(-)-阿拉伯糖醇MSDS

L-(-)-阿拉伯糖醇安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
R20/21/22

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

L-(-)-阿拉伯糖醇合成路线

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L-(-)-阿拉伯糖醇文献

Diagnostic use of cerebral and extracerebral oxysterols.

Clin. Chem. Lab Med. 42(2) , 186-91, (2004)

24S-Hydroxycholesterol (24OHC) and 27-hydroxycholesterol (27OHC) are two structurally similar oxysterols of different origins--the former almost exclusively formed in the brain and the latter formed t...

The effect of increased concentrations of homocysteine on the concentration of (E)-4-hydroxy-2-nonenal in the plasma and cerebrospinal fluid of patients with Alzheimer's disease.

Neurobiol. Aging 23(3) , 383-8, (2002)

There is evidence that increased blood concentrations of homocysteine may be a risk factor for Alzheimer's disease. (E)-4-hydroxy-2-nonenal (HNE) is a neurotoxic product of lipid peroxidation that is ...

Cerebrospinal fluid and plasma distribution of myo-inositol and other polyols in Alzheimer disease.

Clin. Chem. 42(2) , 298-302, (1996)

Previous studies suggest the presence of increased concentrations of cerebral myo-inositol in Alzheimer disease (AD). To characterize this abnormality further, we quantified myo-inositol and several o...

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