氯化钴
氯化钴用途
用作分析试剂及氨吸收剂
【用途二】
用于制造隐显墨水、变色硅胶、干燥剂。
氯化钴名称
[ CAS 号 ]:
7646-79-9
[ 中文名 ]:
二氯化钴
[ 英文名 ]:
Cobalt chloride
[中文别名 ]:
[英文别名 ]:
- EINECS 231-589-4
- dichlorocobalt
- MFCD00010938
- Cobalt(II) chloride
氯化钴物理化学性质
[ 密度 ]:
3.35
[ 沸点 ]:
1049ºC
[ 熔点 ]:
735ºC
[ 分子式 ]:
Cl2Co
[ 分子量 ]:
129.839
[ 闪点 ]:
500°C
[ 精确质量 ]:
128.870911
[ LogP ]:
1.37900
[ 外观性状 ]:
beads
[ 蒸汽压 ]:
33900mmHg at 25°C
[ 储存条件 ]:
2-8°C
[ 水溶解性 ]:
soluble | 不同温度(℃)时每100毫升水中的溶解克数: 43.5g/0℃;47.7g/10℃;52.9g/20℃;59.7g/30℃;69.5g/40℃ 93.8g/60℃;97.6g/80℃;101g/90℃;106g/100℃
氯化钴MSDS
氯化钴毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GF9800000
- CHEMICAL NAME :
- Cobalt(II) chloride
- CAS REGISTRY NUMBER :
- 7646-79-9
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 44
- MOLECULAR FORMULA :
- Cl2-Co
- MOLECULAR WEIGHT :
- 129.83
- WISWESSER LINE NOTATION :
- CO G2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - child
- DOSE/DURATION :
- 48 mg/kg
- TOXIC EFFECTS :
- Behavioral - anorexia (human) Endocrine - thyroid weight (goiter) Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - child
- DOSE/DURATION :
- 1500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - man
- DOSE/DURATION :
- 1042 mg/kg/13W-I
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - optic nerve neuropathy Sense Organs and Special Senses (Eye) - visual field changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 80 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 17402 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4300 ug/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 80 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 49 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 23300 ug/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 36 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1272 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 55 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 165 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 165 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1003 mg/kg/30W-I
- TOXIC EFFECTS :
- Behavioral - alteration of classical conditioning
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 60 mg/kg/3D-I
- TOXIC EFFECTS :
- Behavioral - food intake (animal) Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 1150 mg/kg/10W-I
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Cardiac - other changes Lungs, Thorax, or Respiration - dyspnea
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 400 mg/kg/19D-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 11 mg/kg
- SEX/DURATION :
- female 1-22 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 30 gm/kg
- SEX/DURATION :
- female 15-16 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 7280 mg/kg
- SEX/DURATION :
- male 13 week(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 25 mg/kg
- SEX/DURATION :
- female 10 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)
- TYPE OF TEST :
- Specific locus test
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 750 umol/L
- REFERENCE :
- SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 198,513,1977 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 52,363,1991 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 52,363,1991 IARC Cancer Review:Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 52,363,1991 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84329 No. of Facilities: 267 (estimated) No. of Industries: 13 No. of Occupations: 12 No. of Employees: 2790 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84329 No. of Facilities: 185 (estimated) No. of Industries: 9 No. of Occupations: 13 No. of Employees: 9392 (estimated) No. of Female Employees: 4192 (estimated)
氯化钴安全信息
[ 符号 ]:
GHS05, GHS07, GHS08, GHS09
[ 信号词 ]:
Danger
[ 危害声明 ]:
H302-H317-H318-H334-H341-H350i-H360F-H410
[ 警示性声明 ]:
P201-P261-P273-P280-P284
[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ 危害码 (欧洲) ]:
T:Toxic;N:Dangerousfortheenvironment;
[ 风险声明 (欧洲) ]:
R22;R42/43;R49;R50/53
[ 安全声明 (欧洲) ]:
S22-S45-S53-S60-S61
[ 危险品运输编码 ]:
UN 2923 8/PG 3
[ WGK德国 ]:
2
[ RTECS号 ]:
GF9800000
[ 包装等级 ]:
III
[ 危险类别 ]:
9.0
[ 海关编码 ]:
2827393000
氯化钴合成路线
氯化钴上下游产品
氯化钴上游产品
氯化钴下游产品
氯化钴制备
1.用氯化亚砜与六水氯化钴作用。将20g研细的CoCl2·6H2O放入一只圆底烧瓶中，在室温下加入50mL新蒸馏过的氯化亚砜，立即有SO2和HCl放出，等发泡停息后，在烧瓶上安装一支回流冷凝管，将此混合物回流1～2h，然后将回流管进行改装使之成为蒸馏装置，并在减压下吹入干燥的氮气将多余的氯化亚砜蒸馏出来。将装有产品的烧瓶立即移入一只装有氢氧化钾的真空干燥器中，使之在其中储存至少12h，以除去残余的氯化亚砜。最后在一干燥的操作箱中将产品转移到合适的容器中熔封起来。
氯化钴海关
[ 海关编码 ]: 2827393000
氯化钴文献
Stem Cells Transl. Med. 3(12) , 1514-25, (2014)
Mesenchymal stromal cells (MSCs) have received much attention as a potential treatment of ischemic diseases, including ischemic tissue injury and cardiac failure. The beneficial effects of MSCs are th...
Bilobalide attenuates hypoxia induced oxidative stress, inflammation, and mitochondrial dysfunctions in 3T3-L1 adipocytes via its antioxidant potential.Free Radic. Res. 48(10) , 1206-17, (2014)
Excessive expansion of white adipose tissue leads to hypoxia which is considered as a key factor responsible for adipose tissue dysfunction in obesity. Hypoxia induces inflammation, insulin resistance...
OASIS modulates hypoxia pathway activity to regulate bone angiogenesis.Sci. Rep. 5 , 16455, (2015)
OASIS/CREB3L1, an endoplasmic reticulum (ER)-resident transcription factor, plays important roles in osteoblast differentiation. In this study, we identified new crosstalk between OASIS and the hypoxi...
相关化工产品/化学物质：
推荐生产厂家/供应商：
公司名：上海吉至生化科技有限公司
区域：上海市奉贤区
价格：
￥118.0/25g
￥348.0/100g
联系人：刘佳
产品详情：无水氯化钴(Ⅱ)
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥52.0/5g
￥2100.0/500g
￥188.0/25g
￥需询单/1g
联系人：阿拉丁李高志
产品详情：无水氯化钴(Ⅱ)
公司名：广东翁江化学试剂有限公司
区域：韶关市翁源县
价格：
￥240.0/100ml
￥160.0/100ml
联系人：朱丽丹
产品详情：氯化钴标准溶液
公司名：廊坊乾耀科技有限公司
区域：廊坊市大城县
价格：
￥150.0/500g
￥5000.0/25kg
￥190000.0/1ton
联系人：李菊青
产品详情：无水氯化钴
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相关化合物
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