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丙酰丙嗪

丙酰丙嗪用途

Propionylpromazine hydrochloride (Propiopromazine hydrochloride) 是一种多巴胺受体 D2 (DRD2) 拮抗剂,可用于帕金森氏病的研究。

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丙酰丙嗪名称

[ CAS 号 ]:
7681-67-6

[ 中文名 ]:
盐酸丙酰丙嗪

[ 英文名 ]:
Propionylpromazine hydrochloride

[中文别名 ]:

丙酰丙嗪

[英文别名 ]:

PROPIOPROMAZINE HYDROCHLORIDE
Propionylpromazine hydrochloride

丙酰丙嗪生物活性

[ 描述 ]:

Propionylpromazine hydrochloride (Propiopromazine hydrochloride) 是一种多巴胺受体 D2 (DRD2) 拮抗剂,可用于帕金森氏病的研究。

[ 相关类别 ]:

信号通路 >> G 蛋白偶联受体/G 蛋白 >> 多巴胺受体

信号通路 >> 神经信号通路 >> 多巴胺受体

研究领域 >> 神经疾病

[ 靶点 ]

D2 Receptor

[参考文献]

[1]. Tyers, Mike, et al. Method for treating a brain cancer with ifenprodil. US8058243.

丙酰丙嗪物理化学性质

[ 沸点 ]:
507.4ºC at 760 mmHg

[ 熔点 ]:
90-93ºC

[ 分子式 ]:
C₂₀H₂₅ClN₂OS

[ 分子量 ]:
376.94300

[ 闪点 ]:
260.7ºC

[ 精确质量 ]:
376.13800

[ PSA ]:
48.85000

[ LogP ]:
5.70070

[ 储存条件 ]:
2-8°C

丙酰丙嗪MSDS

详细MSDS(安全技术说明书)

丙酰丙嗪安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 安全声明 (欧洲) ]:
S22

[ 危险品运输编码 ]:
UN 2811

[ WGK德国 ]:
3

丙酰丙嗪文献

Chemical genetics reveals a complex functional ground state of neural stem cells.

Nat. Chem. Biol. 3(5) , 268-273, (2007)

The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc...

Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Nat. Chem. Biol. 5 , 765-71, (2009)

Studies of gene function and molecular mechanisms in Plasmodium falciparum are hampered by difficulties in characterizing and measuring phenotypic differences between individual parasites. We screened...

[Electrocardiography alterations in horses caused by preanesthetic medication with combelen].

Berl. Munch. Tierarztl. Wochenschr. 93(9) , 163-6, (1980)

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