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AH 23848钙盐

AH 23848钙盐用途

AH23848 hemicalcium salt 是一种有效的、特异性的、具有口服活性的血栓素受体 (thromboxane receptor) 阻滞剂。AH23848 hemicalcium salt 抑制血小板沉积。

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AH 23848钙盐名称

[ CAS 号 ]:
81496-19-7

[ 中文名 ]:
AH 23848钙盐

[ 英文名 ]:
AH-23848 calcium salt

[英文别名 ]:

AH 23848钙盐生物活性

[ 描述 ]:

AH23848 hemicalcium salt 是一种有效的、特异性的、具有口服活性的血栓素受体 (thromboxane receptor) 阻滞剂。AH23848 hemicalcium salt 抑制血小板沉积。

[ 相关类别 ]:

研究领域 >> 心血管疾病

信号通路 >> G 蛋白偶联受体/G 蛋白 >> 前列腺素受体

[ 靶点 ]

Thromboxane Receptor[1]

[参考文献]

[1]. Brittain RT, et al. AH23848: a thromboxane receptor-blocking drug that can clarify the pathophysiologic role of thromboxane A2. Circulation. 1985 Dec;72(6):1208-18.

AH 23848钙盐物理化学性质

[ 分子式 ]:
C₅₈H₆₈CaN₂O₁₀

[ 分子量 ]:
993.246

[ 精确质量 ]:
992.450012

[ 储存条件 ]:
-20°C，密闭，干燥

AH 23848钙盐安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

AH 23848钙盐文献

Influence of influenza A infection on capsaicin-induced responses in murine airways.

J. Pharmacol. Exp. Ther. 340 , 377-85, (2012)

The principal aim of the study was to determine the influence of influenza A virus infection on capsaicin-induced relaxation responses in mouse isolated tracheal segments and clarify the underlying me...

The prostaglandin E₂ type 4 receptor participates in the response to acute oxidant stress in airway epithelial cells.

J. Pharmacol. Exp. Ther. 341(2) , 552-63, (2012)

Oxidative stress is implicated in the pathogenesis of many inflammatory pulmonary diseases, including cystic fibrosis (CF). Delineating how oxidative stress stimulates CF transmembrane conductance reg...

The role of cyclooxygenase-2-dependent signaling via cyclic AMP response element activation on aromatase up-regulation by o,p'-DDT in human breast cancer cells.

Toxicol. Lett. 198 , 331-41, (2010)

o,p'-Dichlorodiphenyltrichloroethane (o,p'-DDT) is a DDT isomer and xenoestrogen that can induce inflammation and cancer. However, the effect of o,p'-DDT on aromatase is unclear. Thus, we investigated...

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