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4-溴甲基-6,7-二甲氧基香豆素

4-溴甲基-6,7-二甲氧基香豆素用途

4-溴甲基-6,7-二甲氧基香豆素是色谱检测中羧酸的荧光标记[1]。

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4-溴甲基-6,7-二甲氧基香豆素名称

[ CAS 号 ]:
88404-25-5

[ 中文名 ]:
4-溴甲基-6,7-二甲氧基香豆素

[ 英文名 ]:
4-(Bromomethyl)-6,7-dimethoxy-2H-chromen-2-one

[中文别名 ]:

[英文别名 ]:

4-(Bromomethyl)-6,7-dimethoxy-2H-chromen-2-one
4-(Bromomethyl)-6,7-dimethoxy-2-oxo-2H-benzopyran
MFCD00011570
4-(bromomethyl)-6,7-dimethoxychromen-2-one

4-溴甲基-6,7-二甲氧基香豆素生物活性

[ 描述 ]:

4-溴甲基-6,7-二甲氧基香豆素是色谱检测中羧酸的荧光标记[1]。

[ 相关类别 ]:

研究领域 >> 癌症

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Amet Y, et, al. Simultaneous radiometric and fluorimetric detection of lauric acid metabolites using high-performance liquid chromatography following esterification with 4-bromomethyl-6,7-dimethoxycoumarin in human and rat liver microsomes. J Chromatogr B Biomed Appl. 1996 Jun 7;681(2):233-9.

[2]. R.Farinotti, et al. 4-Bromomethyl-6,7-dimethoxycoumarin as a fluorescent label for carboxylic acids in chromatographic detection. Journal of Chromatography A.Volume 269, 1983, Pages 81-90.

4-溴甲基-6,7-二甲氧基香豆素物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
417.1±45.0 °C at 760 mmHg

[ 熔点 ]:
212-216 °C(lit.)

[ 分子式 ]:
C₁₂H₁₁BrO₄

[ 分子量 ]:
299.117

[ 闪点 ]:
206.0±28.7 °C

[ 精确质量 ]:
297.984070

[ PSA ]:
48.67000

[ LogP ]:
2.70

[ 外观性状 ]:
淡绿色-黄色粉末

[ 蒸汽压 ]:
0.0±1.0 mmHg at 25°C

[ 折射率 ]:
1.579

[ 储存条件 ]:
Refrigerator

[ 水溶解性 ]:
水溶性：不溶

4-溴甲基-6,7-二甲氧基香豆素MSDS

详细MSDS(安全技术说明书)

4-溴甲基-6,7-二甲氧基香豆素安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn: Harmful;C: Corrosive;

[ 风险声明 (欧洲) ]:
R22

[ 安全声明 (欧洲) ]:
S26

[ 危险品运输编码 ]:
1759

[ WGK德国 ]:
3

[ 包装等级 ]:
III

[ 危险类别 ]:
8

[ 海关编码 ]:
2932209090

4-溴甲基-6,7-二甲氧基香豆素上下游产品

4-溴甲基-6,7-二甲氧基香豆素上游产品

4-溴甲基-6,7-二甲氧基香豆素下游产品

4-溴甲基-6,7-二甲氧基香豆素海关

[ 海关编码 ]: 2932209090

[ 中文概述 ]:
2932209090. 其他内酯. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

4-溴甲基-6,7-二甲氧基香豆素文献

Simultaneous radiometric and fluorimetric detection of lauric acid metabolites using high-performance liquid chromatography following esterification with 4-bromomethyl-6,7-dimethoxycoumarin in human and rat liver microsomes.

J. Chromatogr. B, Biomed. Appl. 681(2) , 233-9, (1996)

The formation of (omega-1)-hydroxylauric acid from lauric acid (LA) can be used as an indicator of the activity of cytochrome P450 2E1 (CYP2E1) in rat and human liver microsomes. A high-performance li...

Labeling of immunoglobulins with bifunctional, sulfhydryl-selective, and photoreactive coumarins.

Bioconjug. Chem. 4(4) , 300-4, (1993)

4-(Bromomethyl)-6,7-dimethoxy-2-oxo-2H-benzopyran (1a) and 4-(bromomethyl)-7-methoxy-2-oxo-2H-benzopyran (1b) and their iodo analogs (2) reacted selectively with the sulfhydryl groups generated in a l...

Investigation of derivatization reagents for the analysis of diarrhetic shellfish poisoning toxins by liquid chromatography with fluorescence detection.

Nat. Toxins 2(5) , 302-11, (1994)

Several derivatization reagents for the conversion of okadaic acid and related DSP toxins to fluorescent derivatives for analysis by liquid chromatography have been examined, viz: 9-anthryldiazomethan...

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