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异柠檬酸脱氢酶

异柠檬酸脱氢酶用途

异柠檬酸脱氢酶(ICDH)是一种柠檬酸或三羧酸循环酶,常用于生化研究。异柠檬酸脱氢酶催化异柠檬酸盐氧化脱羧为α-酮戊二酸,并将NAD(P)+还原为NAD(P)H,在细胞代谢中发挥重要作用[1]。

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异柠檬酸脱氢酶名称

[ CAS 号 ]:
9028-48-2

[ 中文名 ]:
异柠檬酸脱氢酶

[ 英文名 ]:
Isocitrate dehydrogenase

[英文别名 ]:

NADP-specific isocitric dehydyrogenase
NADPH-dependent isocitrate dehydrogenase
Oxalosuccinic decarboxylase
TPN-dependent isocitrate dehydrogenase
TPN-isocitrate dehydrogenase
TPN-linked isocitrate dehydrogenase
TPN-specific isocitrate dehydrogenase

异柠檬酸脱氢酶生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> 代谢酶/蛋白酶 >> 异柠檬酸脱氢酶(IDH)

研究领域 >> 代谢疾病

[参考文献]

[1]. Reitman ZJ, Yan H. Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism. J Natl Cancer Inst. 2010 Jul 7;102(13):932-41.

异柠檬酸脱氢酶物理化学性质

[ 外观性状 ]:
液体

[ 储存条件 ]:
2-8°C

异柠檬酸脱氢酶安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ 危险品运输编码 ]:
NONH for all modes of transport

异柠檬酸脱氢酶文献

[Effect of glyphosate on the energy exchange in carp organs].

Ukr. Biokhim. Zh. 85(3) , 22-30, (2013)

The use of glyphosate as a herbicide in agriculture can lead to the presence of its residues and metabolites (aminomethylphosphonic acid) in food for human consumption and pose a threat to health. The...

Genetic features of oligodendrogliomas and presence of seizures. The relationship of seizures and genetics in LGOs.

Clin. Neuropathol. 33(4) , 292-8, (2014)

Low grade oligodendrogliomas (LGO) are diffusely infiltrating World Health Organization (WHO) grade II gliomas, 20 - 30% of which show contrast enhancement. Seizures are a common presenting feature. I...

Controversies over the diagnosis of oligodendroglioma: a report from the satellite workshop at the 4th international symposium of brain tumor pathology, Nagoya Congress Center, May 23, 2012.

Brain Tumor Pathol. 30(4) , 253-61, (2013)

With the goal of discussing how the neuropathology community should resolve the controversy over the diagnosis of oligodendroglioma, this Satellite Workshop reflects the collaboration between two invi...

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