< 生产厂家价格 >

2-甲基喹啉

2-甲基喹啉用途

【用途一】
用作染料、医药中间体
【用途二】
用于制取彩色电影胶片的增碱剂、照相感光剂、橡胶硫化促进剂、润滑油抗氧剂、杀虫剂、杀菌剂以及染料等。

点击显示

2-甲基喹啉名称

[ CAS 号 ]:
91-63-4

[ 中文名 ]:
2-甲基喹啉

[ 英文名 ]:
Quinaldine

[中文别名 ]:

[英文别名 ]:

Quinoline, 2-methyl-
Quinaldine
MFCD00006756
EINECS 202-085-1
2-Methylquinoline
Fasudil Impurity 10

2-甲基喹啉物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
246.5±0.0 °C at 760 mmHg

[ 熔点 ]:
-2 °C

[ 分子式 ]:
C₁₀H₉N

[ 分子量 ]:
143.185

[ 闪点 ]:
79.4±0.0 °C

[ 精确质量 ]:
143.073502

[ PSA ]:
12.89000

[ LogP ]:
2.54

[ 外观性状 ]:
淡黄色

[ 蒸汽压 ]:
0.0±0.4 mmHg at 25°C

[ 折射率 ]:
1.625

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开储运

[ 稳定性 ]:
Stable, but may be light sensitive. Combustible. Incompatible with strong oxidizing agents.

[ 水溶解性 ]:
PRACTICALLY INSOLUBLE

2-甲基喹啉MSDS

2-甲基喹啉毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UZ9625000

CHEMICAL NAME :: Quinaldine

CAS REGISTRY NUMBER :: 91-63-4

BEILSTEIN REFERENCE NO. :: 0110309

LAST UPDATED :: 199806

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C10-H9-N

MOLECULAR WEIGHT :: 143.20

WISWESSER LINE NOTATION :: T66 BNJ C1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1230 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1870 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 2 umol/plate

REFERENCE :: CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 36,4630,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0823 No. of Facilities: 33 (estimated) No. of Industries: 1 No. of Occupations: 4 No. of Employees: 28314 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T0823 No. of Facilities: 514 (estimated) No. of Industries: 9 No. of Occupations: 12 No. of Employees: 4782 (estimated) No. of Female Employees: 1548 (estimated)

点击显示

2-甲基喹啉安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302 + H312

[ 警示性声明 ]:
P280

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R21/22;R36/37/38;R68

[ 安全声明 (欧洲) ]:
S36-S45-S36/37/39-S26

[ 危险品运输编码 ]:
2810.0

[ WGK德国 ]:
3

[ RTECS号 ]:
UZ9625000

[ 危险类别 ]:
6.1

[ 海关编码 ]:
29334990

2-甲基喹啉合成路线

2-甲基喹啉上下游产品

2-甲基喹啉上游产品

2-甲基喹啉下游产品

2-甲基喹啉制备

可从煤焦油中提取也可采用合成法制备。萘油馏分和洗油馏分经用硫酸洗涤得到的硫酸喹啉盐基溶液，用蒸气蒸吹除去中性油等杂质，再用碱或氨分解，分离出来的粗喹啉及基同系物经脱水后，用60块理论塔板的高效蒸馏塔精馏，切取基中沸程为237.5-239.5℃的馏分段，可以得到的粗喹啉；继续切取沸程为243-246℃的馏分段，作为提取异喹啉和2-甲基喹啉的原料；继续切取260-267℃的馏分段，作为提取4-甲基喹啉的原料。243-246℃的馏分以盐酸化物形态分离出2-甲基喹啉，将2-甲基喹啉盐酸化物结晶用苯洗涤，再用20%的氢氧化钠溶液将盐分解，精馏切取246.6-247.4℃馏分，可得纯度大于95%的2-甲基喹啉。由苯胺与2，3-二溴丁醛反应可合成得到2-甲基喹啉。

点击显示

2-甲基喹啉海关

[ 海关编码 ]: 2933499090

[ 中文概述 ]:
2933499090. 其他含喹琳或异喹啉环系的化合物〔但未进一步稠合的〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2-甲基喹啉文献

The PaaX-type repressor MeqR2 of Arthrobacter sp. strain Rue61a, involved in the regulation of quinaldine catabolism, binds to its own promoter and to catabolic promoters and specifically responds to anthraniloyl coenzyme A.

J. Bacteriol. 195(5) , 1068-80, (2013)

The genes coding for quinaldine catabolism in Arthrobacter sp. strain Rue61a are clustered on the linear plasmid pAL1 in two upper pathway operons (meqABC and meqDEF) coding for quinaldine conversion ...

Quantitative structure-activity relationship analysis of inhibitors of the nicotine metabolizing CYP2A6 enzyme.

J. Med. Chem. 48 , 440-9, (2005)

The purpose of this study was to develop screening and in silico modeling methods to obtain accurate information on the active center of CYP2A6, a nicotine oxidizing enzyme. The inhibitory potencies o...

Exploring QSAR and QAAR for inhibitors of cytochrome P450 2A6 and 2A5 enzymes using GFA and G/PLS techniques

Eur. J. Med. Chem. 44 , 1941-51, (2009)

A series of naphthalene and non-naphthalene derivatives ( n = 42) having cytochrome P450 2A6 and 2A5 inhibitory activities, reported by Rahnasto et al., were subjected to QSAR and QAAR studies. The an...

更多文献

2-甲基喹啉

2-甲基喹啉用途

2-甲基喹啉名称

2-甲基喹啉物理化学性质

2-甲基喹啉MSDS

详细MSDS(安全技术说明书)

2-甲基喹啉毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

2-甲基喹啉安全信息

2-甲基喹啉合成路线

详细合成路线

2-甲基喹啉上下游产品

2-甲基喹啉上游产品

2-甲基喹啉下游产品

2-甲基喹啉制备

2-甲基喹啉海关

2-甲基喹啉文献

相关化工产品/化学物质：

推荐生产厂家/供应商：

相关化合物