2-甲基喹啉
一般危化品
2-甲基喹啉结构式
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常用名 | 2-甲基喹啉 | 英文名 | Quinaldine |
|---|---|---|---|---|
| CAS号 | 91-63-4 | 分子量 | 143.185 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 246.5±0.0 °C at 760 mmHg | |
| 分子式 | C10H9N | 熔点 | -2 °C | |
| MSDS | 中文版 美版 | 闪点 | 79.4±0.0 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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The PaaX-type repressor MeqR2 of Arthrobacter sp. strain Rue61a, involved in the regulation of quinaldine catabolism, binds to its own promoter and to catabolic promoters and specifically responds to anthraniloyl coenzyme A.
J. Bacteriol. 195(5) , 1068-80, (2013) The genes coding for quinaldine catabolism in Arthrobacter sp. strain Rue61a are clustered on the linear plasmid pAL1 in two upper pathway operons (meqABC and meqDEF) coding for quinaldine conversion to anthranilate and a lower pathway operon encoding anthran... |
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Quantitative structure-activity relationship analysis of inhibitors of the nicotine metabolizing CYP2A6 enzyme.
J. Med. Chem. 48 , 440-9, (2005) The purpose of this study was to develop screening and in silico modeling methods to obtain accurate information on the active center of CYP2A6, a nicotine oxidizing enzyme. The inhibitory potencies of 26 naphthalene and 16 non-naphthalene derivatives were de... |
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Exploring QSAR and QAAR for inhibitors of cytochrome P450 2A6 and 2A5 enzymes using GFA and G/PLS techniques
Eur. J. Med. Chem. 44 , 1941-51, (2009) A series of naphthalene and non-naphthalene derivatives ( n = 42) having cytochrome P450 2A6 and 2A5 inhibitory activities, reported by Rahnasto et al., were subjected to QSAR and QAAR studies. The analyses were performed using electronic, spatial, shape and ... |
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Predictive three-dimensional quantitative structure-activity relationship of cytochrome P450 1A2 inhibitors.
J. Med. Chem. 48 , 3808-15, (2005) The purpose of this study was to determine the cytochrome P450 1A2 (CYP1A2) inhibition potencies of structurally diverse compounds to create a comprehensive three-dimensional quantitative structure-activity relationship (3D-QSAR) model of CYP1A2 inhibitors an... |
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A fluorometric assay for the determination of 1-deoxy-D-xylulose 5-phosphate synthase activity.
Anal. Biochem. 296(1) , 101-5, (2001) We report a novel fluorometric end-point assay for the determination of 1-deoxy-d-xylulose 5-phosphate synthase (DXS) activity based on the reaction of 1-deoxy-D-xylulose 5-phosphate (DX5P) with 3,5-diaminobenzoic acid in an acidic medium to form a highly flu... |
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Synthesis and SAR study of acridine, 2-methylquinoline and 2-phenylquinazoline analogues as anti-prion agents.
Eur. J. Med. Chem. 41(10) , 1124-43, (2006) Transmissible spongiform encephalopathies (TSEs) are thought to arise from aggregation of a protease resistant protein denoted PrP(Sc), which is a misfolded isoform of the normal cellular prion protein PrP(C). Using virtual high-throughput screening we have s... |
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Selective binding of coumarin enantiomers to human alpha1-acid glycoprotein genetic variants.
Bioorg. Med. Chem. 14(6) , 1959-65, (2006) Coumarin-type anticoagulants, warfarin, phenprocoumon and acenocoumarol, were tested for their stereoselective binding to the human orosomucoid (ORM; AGP) genetic variants ORM 1 and ORM 2. Direct binding studies with racemic ligands were carried out by the ul... |
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Terahertz absorption spectroscopy of a liquid using a polarity probe: a case study of trehalose/water mixtures.
Angew. Chem. Int. Ed. Engl. 49(2) , 454-7, (2010)
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A "jellyfish" shaped green emitting gallium(III)-containing metallomesogen.
Chem. Commun. (Camb.) (19) , 2254-6, (2008) The synthesis of the first gallium(III)-based liquid crystal has been achieved grafting around the metal centre two chelating 2-methylquinolin-8-olate anions and one monodentate 3,4,5-tris(hexadecyloxy)benzoyloxy ligand, allowing the resulting complex to be a... |
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Blue emitting pentacoordinated Al(III) complexes based on 2-methylquinolin-8-olate and substituted phenolate ligands. The role of phenolate derivatives on emission and absorption properties.
Dalton Trans. (2) , 330-9, (2006) This paper reports the synthesis, characterisation and photophysical investigation of the homologous series of blue-emitting pentacoordinated AlQ'(2)L complexes 1-6, where Q' is 2-methylquinolin-8-olate and L is a phenolate substituted in para to the oxygen d... |