三氟甲苯

三氟甲苯用途

【用途一】
用途：用于制造药物、染料，并用作硫化剂、杀虫剂等
【用途二】
三氟甲基苯是氟化学中重要中间体，可以制备氟草隆、氟咯草酮、吡氟草胺等除草剂，也是医药的重要中间体。
【用途三】
医药、染料的中间体，溶剂。并用作硫化剂及绝缘油的制造。
【用途四】
医药；染料的中间体，溶剂。并用作硫化剂及绝缘油的制造。

点击显示

三氟甲苯名称

[ CAS 号 ]:
98-08-8

[ 中文名 ]:
三氟甲苯

[ 英文名 ]:
Benzotrifluoride

[中文别名 ]:

[英文别名 ]:

Triflorotoluene
(Trifluoromethyl)benzene
benzenylfluoride
Trifluoromethylbenzene
Benzotrifluoide
Trifluoromethyl-benzene
Benzotrifluoride
3-trifluoromethyl-benzene
EINECS 202-635-0
Oxsol2000

三氟甲苯物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
104.8±35.0 °C at 760 mmHg

[ 熔点 ]:
−29 °C(lit.)

[ 分子式 ]:
C₇H₅F₃

[ 分子量 ]:
146.110

[ 闪点 ]:
12.2±0.0 °C

[ 精确质量 ]:
146.034332

[ LogP ]:
2.79

[ 外观性状 ]:
透明液体带有芳香气味

[ 蒸汽压 ]:
35.3±0.2 mmHg at 25°C

[ 折射率 ]:
1.422

[ 储存条件 ]:
库房通风低温干燥,与氧化剂、酸类分开存放

[ 稳定性 ]:
Stable. Highly flammable. Incompatible with strong oxidizing agents, strong bases, strong reducing agents.

[ 水溶解性 ]:
<0.1 g/100 mL at 21 ºC

三氟甲苯MSDS

三氟甲苯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XT9450000

CHEMICAL NAME :: Toluene, alpha,alpha,alpha-trifluoro-

CAS REGISTRY NUMBER :: 98-08-8

BEILSTEIN REFERENCE NO. :: 1906908

LAST UPDATED :: 199710

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C7-H5-F3

MOLECULAR WEIGHT :: 146.12

WISWESSER LINE NOTATION :: FXFFR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 15 gm/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Behavioral - excitement Behavioral - muscle weakness

REFERENCE :: TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 10,131,1968

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 70810 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,25,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 10000 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Behavioral - excitement Behavioral - muscle weakness

REFERENCE :: TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 10,131,1968

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 92240 mg/m3/2H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,25,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Amphibian - frog

DOSE/DURATION :: 870 mg/kg

TOXIC EFFECTS :: Autonomic Nervous System - other (direct) parasympathomimetic

REFERENCE :: AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 130,250,1928

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 92 gm/m3

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 30(3),6,1986 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 15500 mg/kg/7W-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - proteinuria Kidney, Ureter, Bladder - other changes in urine composition

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 50(2),86,1985 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 100 mg/m3 JAN 1993

点击显示

三氟甲苯安全信息

[ 符号 ]:

GHS02, GHS07, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H304-H315-H319-H340-H350-H372

[ 警示性声明 ]:
P201-P210-P280-P308 + P313-P370 + P378-P403 + P235

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
F:Flammable

[ 风险声明 (欧洲) ]:
R11;R51/53

[ 安全声明 (欧洲) ]:
S53-S26-S36/37-S45-S62-S61-S23-S16

[ 危险品运输编码 ]:
UN 2338 3/PG 2

[ WGK德国 ]:
3

[ RTECS号 ]:
XT9450000

[ 包装等级 ]:
II

[ 危险类别 ]:
3

[ 海关编码 ]:
2903999090

三氟甲苯合成路线

三氟甲苯上下游产品

三氟甲苯上游产品

三氟甲苯下游产品

三氟甲苯制备

1、由ω,ω,ω-三氯甲苯与无水氟化氢作用而得。ω,ω,ω-三氯甲苯与无水氟化氢的摩尔配比为1：3.88，反应在温度为80-104℃，压力为1.67-1.77MPa下进行2-3h。收率为72.1%。由于无水氟化氢便宜易得，设备易解决，不需特殊钢材，成本低，适合工业化。

2、由ω,ω,ω-三氟甲苯与三氟化锑作用而得。将ωωω三氟甲苯和三氟化锑放在反应锅内加热蒸馏，馏出液即三氟甲基苯粗品。用5%盐酸洗涤，再加5%氢氧化钠溶液，加热蒸馏，收集80-105℃馏分。分去上层液，下层液用无水氯化钙干燥，过滤后得三氟甲基苯。收率75%。此法耗用锑化物，成本较高，一般只在实验室条件下采用比较方便。

3、其制备方法是以甲苯为原料，先用氯气在催化剂存在下侧链氯化，得α，α，α-三氯甲苯，然后与氟化氢反应得产品。

点击显示

三氟甲苯海关

[ 海关编码 ]: 2903999090

[ 中文概述 ]:
2903999090 其他芳烃卤化衍生物. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:5.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

三氟甲苯文献

Utilizing capillary gas chromatography mass spectrometry to determine 4-benzotrifluoride t-butyl ether as a reaction by-product in fluoxetine synthesized using potassium t-butoxide as base.

J. Pharm. Biomed. Anal. 31(1) , 63-74, (2003)

Fluoxetine hydrochloride has been prepared using two similar synthetic routes, both of which rely upon an ether formation reaction mediated by a base. The base used can affect the impurity profile of ...

Study of the voltammetric behaviour of the ethalfluralin and methalpropalin and its determination in environmental matrices at hanging mercury drop electrode.

Environ. Monit. Assess. 151(1-4) , 9-18, (2009)

An electroanalytical method has been developed for the determination of the herbicides ethalfluralin[N-ethyl-N-(2-methyl-2-propenyl)-2,6-dinitro-4-(trifluoromethyl) bezenamine] and methalpropalin [N-(...

Precursor chemistry matters in boosting photoredox activity of graphene/semiconductor composites.

Nanoscale 7 , 18062-70, (2015)

Considerable effort has been made to fabricate graphene (GR)/semiconductor composite photocatalysts, by using graphene oxide (GO) as the most widely used precursor of GR, toward an improved efficacy o...

更多文献

三氟甲苯

三氟甲苯用途

三氟甲苯名称

三氟甲苯物理化学性质

三氟甲苯MSDS

详细MSDS(安全技术说明书)

三氟甲苯毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

三氟甲苯安全信息

三氟甲苯合成路线

详细合成路线

三氟甲苯上下游产品

三氟甲苯上游产品

三氟甲苯下游产品

三氟甲苯制备

三氟甲苯海关

三氟甲苯文献

相关化工产品/化学物质：

推荐生产厂家/供应商：

相关化合物