那格列奈相关物质C结构式
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常用名 | 那格列奈相关物质C | 英文名 | D-Phenylalanine, N-[[4-(1-methylethyl)cyclohexyl]carbonyl]-, cis- |
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| CAS号 | 105816-06-6 | 分子量 | 317.42300 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C19H27NO3 | 熔点 | N/A | |
| MSDS | N/A | 闪点 | N/A |
| 中文名 | 那格列奈相关物质C |
|---|---|
| 英文名 | Nateglinide Related CoMpound C |
| 分子式 | C19H27NO3 |
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| 分子量 | 317.42300 |
| 精确质量 | 317.19900 |
| PSA | 66.40000 |
| LogP | 3.65180 |
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Formulation and in vitro evaluation of nateglinide microspheres using HPMC and carbopol-940 polymers by ionic gelation method.
Pak. J. Pharm. Sci. 26(6) , 1229-35, (2013) This study involves the design and characterization of Nateglinide (NAT) microspheres to enhance patient compliance. Ionic gelation technique was used to prepare Nateglinide Microspheres by using rate... |
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II. Technological approaches to improve the dissolution behavior of nateglinide, a lipophilic insoluble drug: co-milling.
Int. J. Pharm. 454(1) , 568-72, (2013) Nateglinide is an oral antidiabetic agent that should be administered 10-30 min before the meal, but it shows low and pH-dependent solubility that may reduce its oral bioavailability. To improve nateg... |
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I. Technological approaches to improve the dissolution behavior of nateglinide, a lipophilic insoluble drug: nanoparticles and co-mixing.
Int. J. Pharm. 454(1) , 562-7, (2013) Nateglinide is a non-sulphonylurea insulinotropic oral antidiabetic agent. The main problem in formulating an oral dosage form is its low solubility in aqueous media. This problem is particularly crit... |
