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2-巯(基)嘌呤

2-巯(基)嘌呤结构式
2-巯(基)嘌呤结构式
品牌特惠专场
常用名 2-巯(基)嘌呤 英文名 2H-Purine-2-thione,3,9-dihydro-
CAS号 28128-19-0 分子量 152.17700
密度 1.82g/cm3 沸点 498.6ºC at 760mmHg
分子式 C5H4N4S 熔点 N/A
MSDS 中文版 美版 闪点 255.4ºC
符号 GHS05 GHS07
GHS05, GHS07
信号词 Danger

Analysis of phenolic compounds in the dissolved and suspended phases of Lake Balaton water by gas chromatography-tandem mass spectrometry.

Environ. Sci. Pollut. Res. Int. 22 , 11966-74, (2015)

As a novel approach to characterize the phenolic pollutants of Lake Balaton (Central Europe, western Hungary), 26 endocrine disrupting phenols (chlorophenols, nitrophenols, alkylphenols, triclosan, bisphenol-A) were quantified in dissolved and suspended parti...

Rate Coefficients for the Gas-Phase Reactions of Hydroxyl Radicals with a Series of Methoxylated Aromatic Compounds.

J. Phys. Chem. A 119 , 6179-87, (2015)

Rate coefficients for the reactions of hydroxyl radicals (OH) with a series of oxygenated aromatics (two methoxybenzene and five methoxyphenol isomers) have been obtained using the relative kinetic method in 1080 and 480 L photoreactors at the University of W...

6-Mercaptopurine decreases the Bcl-2/Bax ratio and induces apoptosis in activated splenic B lymphocytes.

Mol. Pharmacol. 51 , 414-421, (1997)

6-Mercaptopurine and related purine antimetabolites are used in the treatment of several B cell disorders. These drugs inhibited the proliferation of mature splenic B cells after being triggered with polyclonal mitogens. In addition to the antiproliferative e...

Kinetics of oxidation of aliphatic and aromatic thiols by myeloperoxidase compounds I and II.

FEBS Lett. 443 , 290-296, (1999)

Myeloperoxidase (MPO) is the most abundant protein in neutrophils and plays a central role in microbial killing and inflammatory tissue damage. Because most of the non-steroidal anti-inflammatory drugs and other drugs contain a thiol group, it is necessary to...

Nature and position of functional group on thiopurine substrates influence activity of xanthine oxidase--enzymatic reaction pathways of 6-mercaptopurine and 2-mercaptopurine are different.

Biochemistry. (Mosc.) 72 , 170-177, (2007)

Xanthine oxidase-catalyzed hydroxylation reactions of the anticancer drug 6-mercaptopurine (6-MP) and its analog 2-mercaptopurine (2-MP) as well as 6-thioxanthine (6-TX) and 2-thioxanthine (2-TX) have been studied using UV-spectroscopy, high pressure liquid c...