阿维A酸结构式
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常用名 | 阿维A酸 | 英文名 | Acitretin |
|---|---|---|---|---|
| CAS号 | 55079-83-9 | 分子量 | 326.429 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 521.3±38.0 °C at 760 mmHg | |
| 分子式 | C21H26O3 | 熔点 | 228-230ºC | |
| MSDS | 美版 | 闪点 | 180.3±20.3 °C | |
| 符号 |
GHS07, GHS08, GHS09 |
信号词 | Danger |
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Comparative effectiveness of less commonly used systemic monotherapies and common combination therapies for moderate to severe psoriasis in the clinical setting.
J. Am. Acad. Dermatol. 71(6) , 1167-75, (2014) The effectiveness of psoriasis therapies in real-world settings remains relatively unknown.We sought to compare the effectiveness of less commonly used systemic therapies and commonly used combination therapies for psoriasis.This was a multicenter cross-secti... |
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Acitretin exhibits inhibitory effects towards UDP-glucuronosyltransferase (UGT)1A9-mediated 4-methylumbelliferone (4-MU) and propofol glucuronidation reaction.
Pharmazie 68(6) , 449-52, (2013) The present study aimed to evaluate the potential risk of drug-drug interactions associated with acitretin which is a drug for therapy of psoriasis approved by the Food and Drug Administration (FDA). The initial screening of acitretin's inhibition towards 4-m... |
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IgA pemphigus: case series with emphasis on therapeutic response.
J. Am. Acad. Dermatol. 70(1) , 200-1, (2014)
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Systemic retinoids in the management of ichthyoses and related skin types.
Dermatol. Ther. 26(1) , 26-38, (2013) The term retinoid includes both natural and synthetic derivatives of vitamin A. Retinoid-containing treatments have been used since ~1550BC by the early Egyptians. Treatment of ichthyosiform disorders with retinoids dates back at least to the 1930s. Early use... |
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From the Medical Board of the National Psoriasis Foundation: The risk of cardiovascular disease in individuals with psoriasis and the potential impact of current therapies.
J. Am. Acad. Dermatol. 70(1) , 168-77, (2014) Many studies have identified cardiovascular risk factors in patients with psoriasis. Some psoriasis therapies may increase cardiovascular disease (CVD) and others may decrease CVD.We reviewed the literature to define the impact of common psoriasis therapies o... |
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Cytotoxic and genotoxic effects of acitretin, alone or in combination with psoralen-ultraviolet A or narrow-band ultraviolet B-therapy in psoriatic patients.
Mutat. Res. 753(1) , 42-7, (2013) Acitretin is currently used alone or combined with PUVA (psoralen + UVA) or with narrow-band ultraviolet B (NBUVB), to treat moderate and severe psoriasis. However, little is known about the potential genotoxic/carcinogenic risk and the cytostatic/cytotoxic e... |
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A high-content assay to identify small-molecule modulators of a cancer stem cell population in luminal breast cancer.
J. Biomol. Screen. 17(9) , 1211-20, (2012) Breast cancers expressing hormone receptors for estrogen (ER) and progesterone (PR) represent ~70% of all cases and are treated with both ER-targeted and chemotherapies, with near 40% becoming resistant. We have previously described that in some ER(+) tumors,... |
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Pseudoainhum in acute psoriasis.
J. Coll. Physicians Surg. Pak. 22(12) , 786-8, (2012) The term Pseudoainhum is used in medical literature to elaborate the presence of constricting bands around the digits of hands and feet due to variety of etiologies. This phenomenon can lead to irreversible damage to the supplying neurovasculature and sequent... |
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Therapeutic combination of radiofrequency surgical dissection and oral acitretin in the management of perianal Buschke-Lowenstein tumour: a case report.
Int. J. STD AIDS 23(5) , 362-4, (2012) Giant condyloma acuminatum (GCA), or Buschke-Löwenstein tumour (BLT), is a rare large tumour of the anogenital area. It is caused by human papillomavirus genotypes 6 and 11, and it is characterized by aggressive local invasion and frequent recurrences after t... |
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Complete and rapid regression of primary cutaneous follicular lymphoma with repeated oral administration of acitretin for palmoplantar psoriasis.
J. Am. Acad. Dermatol. 69(4) , e176-7, (2013)
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